OUR Archive (Otago University Research Archive)
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Identifying the role of connexin 43 in transport of microRNAs
Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Present treatments for CVD rely heavily on surgical interventions and drug therapies that relieve symptoms rather than cure the disease. Therefore, ... -
The Impact of Epithelial Sodium Channel on Breast Cancer Cell Migration
Breast cancer is the most common cancer in New Zealand women, with the majority of breast cancer deaths being due to metastasis. This highlights the importance of identifying regulators and, thus, potential therapeutic ... -
Sodium and Uric Acid as Modulators of Vascular Endothelial ENaC
Hypertension, defined as a chronically high blood pressure, is a significant risk factor for heart attacks and strokes. Despite hypertension affecting 28% of individuals over the age of 20 years old, little is known about ... -
Modulation of Lineage Development in the Colonic Epithelium
Despite being exposed to microbial and food antigens, the human gastrointestinal tract does not exist in a state of inflammation. This homeostasis is critically dependent on the colonic epithelial barrier, which when ... -
Investigating the Effects of Chronic Low-Grade Inflammation on Cancer Immunotherapy
Cancer is the leading cause of death in New Zealand and is responsible for approximately one third of all deaths. Due to various factors, including unhealthy life style choices and an aging population, the number of new ...