Browsing by Author "Feng, Feifei"
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In vitro and in vivo studies on the binding and permeation of ketotifen and norketotifen atropisomers in the central nervous system
Feng, FeifeiKetotifen (K) is a first-generation antihistamine with antiinflammatory potency. It penetrates the blood-brain barrier (BBB) and causes a sedative side effect. Norketotifen (N) is an active metabolite of K. The S-atropisomer ...