Search
Now showing items 5551-5560 of 6687
Effects of OTX008, a galectin-1 inhibitor, on oral squamous cell carcinoma cells in vitro
Oral squamous cell carcinoma (OSCC) is a common cancer that is currently associated with significant morbidity and poor mortality, and for which targeted therapeutics have yet to be proved effective. Galectin-1 is a ...
Novel methods for influenza drug research and development: Cloning, expression and purification of influenza neuraminidase for inhibitory assays
Influenza is a highly contagious virus which can cause mild to severe disease. The most effective drugs for treating influenza, are the neuraminidase inhibitors (NAIs), but resistance to these inhibitors has emerged. New ...
Crowdsourcing vs. Citizen Science: A matter of terminology?
Businesses have sought to create real dialogue with their customers and gain new insights from them through this dialogue. Outsourcing some of their processes to their consumer base is one way they can form a stronger ...
The Sublime and Sensibility in French Keyboard Music in the Late Seventeenth and Early Eighteenth Centuries
This dissertation examines the aesthetic elements of the keyboard music from the late seventeenth and early eighteenth centuries in France, highlighting the concepts of the Sublime and Sensibility. In order to evaluate the ...
Buildings Archaeology and Elite Housing in 19th Century Christchurch
The field of buildings archaeology in New Zealand is understudied and has resulted in the provision of architectural history rather than an archaeological investigation into what the design of the buildings tells us about ...
The role of the SVP gene family in controlling bud dormancy
SHORT VEGETATIVE PHASE (SVP)-like genes in the StMADS11 gene family have roles in the regulation of flowering time in annual plants and there is evidence that they also function in the regulation of dormancy in perennials. ...
Roles of Introns
Many genes of eukaryotes and viruses contain introns. The roles of introns are not fully understood because many of them seem dispensable. To address this long-standing question, comparative genomics and ‘multi-omic’ ...
The development and characterization of a new mouse model of Alzheimer’s disease
Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder characterized by progressive memory loss, seizures, anxiety, personality changes and ultimately, death. Current animal models of AD have not yielded any ...
Essays on Gender and the Macroeconomy
The discourse on gender equality is one that has become increasingly popular in economic research and policy considerations. A large strand of this discourse appeals to the ideals of human dignity, societal welfare, fairness ...
Mining bioactive peptides from sheep cheese whey β-lactoglobulin using food grade proteases
Sheep cheese whey (SCW) is a by-product of the cheese making process that is often considered waste and treated as an environmental pollutant. This research project stemmed from a recent change in view that rather than ...