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Investigating the activation of nucleus accumbens projective paraventricular nucleus of the thalamus during cue-food reward conditioning
When a previously neutral cue is learnt to predict a food reward, the presence of the cue itself can elicit the motivation to obtain the food. The nucleus accumbens shell (nAccSh) in the mesolimbic system is involved in ...
Survival, not resilience: Young people's housing instability
Young people’s experiences of housing instability need to be recognised. The extant literature tends to equate young people’s experiences with that of adults and the limited literature that exclusively examines young people ...
Effects of the COVID-19 lockdown on the healthcare experiences of medical crowdfunders in Aotearoa New Zealand
New Zealand went into a strict, nation-wide lockdown at 11:59pm, on Wednesday the 25th of March 2020, in an early effort to stem community transmission of – and later, eliminate – COVID-19. This lockdown was justified by ...
Mechanisms of bactericidal action and β-lactam synergy by the zinc ionophore PBT2
The emergence and global spread of antimicrobial resistance (AMR) is an increasingly serious threat to human and veterinary medicine. Driven by the misuse and overuse of antibiotics, resistance to our antibiotic armoury ...
Learning Gene Interactions and Networks from Perturbation Screens and Expression Data
We investigate a variety of methods to first discover and then understand genetic interactions. Beginning with pairwise interactions, we propose a method for inferring pairwise gene interactions en masse from short- ...
Myofilament Mechanisms Underlie Changes of Diabetic Cardiac Impairment
The myofilament protein, cardiac troponin I (cTnI), is a critical regulatory protein in the contraction and relaxation of cardiac muscle, linking calcium to bind to the thin filament. It has become apparent that myofilament ...
Investigating RNF43 Mutations as Biomarkers for ctDNA Surveillance of Colorectal Cancer
This project aimed to investigate the utility of RNF43 mutations for circulating tumour DNA (ctDNA) surveillance of colorectal cancer (CRC). CRC is the second deadliest cancer in New Zealand. CRC patients currently under-go ...
Nematic spin vortices in spin-1 Bose-Einstein condensates
Spin-1 Bose-Einstein condensates present a wealth of physics, owing to the spin and superfluid order they possess. In this work, we consider spin-1 condensates with antiferromagnetic interactions, which favor the formation ...
Advocacy for Using Evidence in Public Health Nutrition Policy Making
Do advocates for using evidence make a difference? A case study of public health nutrition policymaking in New Zealand.
There is a growing body of evidence supporting interventions that will effectively address nutrition-related ...