Abstract
Substance use disorder (SUD) has a large impact on both the medical system and society. Stress, craving and triggers lead to relapse in 85% patients with alcohol SUD within one year of traditional treatments. The DLPFC has been most targeted for non-invasive transcranial stimulation, and the insula may be an emerging target. Meta-analyses of non-invasive high frequency rTMS of the left DLPFC and bifrontal tDCS demonstrate beneficial effects on craving and consumption. The ACC has been targeted to reduce craving and stress in different addictive disorders, both by lesioning and neuromodulation. Neuromodulation of the ACC has been performed with non-invasive transcranial magnetic stimulation and transcranial direct current stimulation, as well as invasively by implanted electrodes. But no meta-analysis has been performed. An addiction/craving network can be targeted at multiple parts of the cortex, including the DLPFC, ACC, and insula.
Breakout Session - Brain: Neuropsychiatry: Novel Applications In Behavioral Neuromodulation