Non thymic origin of lymphocytes mediating antibody induced cytotoxicity against tumour cells

N. Matthews; B.P. Maclaurin

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Non thymic origin of lymphocytes mediating antibody induced cytotoxicity against tumour cells

Conference proceeding

Peer reviewed

Non thymic origin of lymphocytes mediating antibody induced cytotoxicity against tumour cells

N. Matthews and B.P. Maclaurin

Proceedings of the University of Otago Medical School, Vol.51(1), pp.13-15

Proceedings of the University of Otago Medical School

1973

Handle:

https://hdl.handle.net/10523/12990

Abstract

antibody

cytotoxic antibody

B lymphocyte

cancer cell

cancer immunology

cytotoxicity

lymphocyte

rat

theoretical study

The results are similar to those of previous studies employing adult thymectomy plus irradiation and confirm that T lymphocytes are not the effector cells in antibody induced, lymphocyte mediated cytotoxicity (ALC). Accordingly, cytotoxicity in this system is presumed to be dependent on bone marrow derived (B) lymphocytes. The higher proportion of B lymphocytes in spleen cells from thymectomised animals would account for the increased ALC capacity demonstrated.

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Record Identifier: 9926479924701891
Title: Non thymic origin of lymphocytes mediating antibody induced cytotoxicity against tumour cells
Creators: N. Matthews
B.P. Maclaurin
Publication Details: Proceedings of the University of Otago Medical School, Vol.51(1), pp.13-15
Academic Unit: Otago Medical School Research Society
Publisher: Otago Medical School Research Society
Date published ; e-published: 1973
Date copyright: 1973
Comment: Abstract presented at Otago Medical Research Society meeting. There is no published article available. If abstract text is digitally available, it will be included in this record. This item is available in holdings at University of Otago Libraries. See https://otago.primo.exlibrisgroup.com/permalink/64OTAGO_INST/qef3lj/alma9911647701891 for more information.
Language: English
Resource Type; Subtype: Conference proceeding

Non thymic origin of lymphocytes mediating antibody induced cytotoxicity against tumour cells

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