Abstract
I have been part of this field since the early days and seen its expansion from what was initially considered as an esoteric topic to a discipline that impacts on a multitude of aspects of cell biology and disease pathology. With the impetus largely being the discovery of superoxide dismutase, we started with a strong focus on superoxide and understanding the consequences of free radical exposure to life. Since then we have seen the field expand to cover a wider range of radical and non-radical oxidants, and come to appreciation that redox biology is important in physiology as well as pathology and toxicology. I will discuss some of the milestones that influenced my thinking and the direction of the field.
Lecture presentation.