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The binding of sodium aurothiomalate to Mycoplasma arthritidis
Conference proceeding   Peer reviewed

The binding of sodium aurothiomalate to Mycoplasma arthritidis

H.L. Talbot and D.B. Myers
Proceedings of the University of Otago Medical School, Vol.54(2), pp.55-56
Proceedings of the University of Otago Medical School
1976
Handle:
https://hdl.handle.net/10523/13101

Abstract

aurothiomalate aurothiomalate sodium au 195 radioisotope unclassified drug drug binding in vitro study microorganism Mycoplasma arthritidis theoretical study
It has been suggested that a member of the mycoplasma group of organisms could play an etiological role in rheumatoid arthritis. Sodium aurothiomalate (ATM), a known inhibitor of mycoplasmas, is used to treat rheumatoid arthritis although its mode of action in alleviating this disorder is unknown. In this paper we report the binding of radioactive ATM to whole organisms and membrane fragments obtained from cultures of Mycoplasma arthritidis, a species which produces polyarthritis in rats.

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