Abstract
It has been suggested that a member of the mycoplasma group of organisms could play an etiological role in rheumatoid arthritis. Sodium aurothiomalate (ATM), a known inhibitor of mycoplasmas, is used to treat rheumatoid arthritis although its mode of action in alleviating this disorder is unknown.
In this paper we report the binding of radioactive ATM to whole organisms and membrane fragments obtained from cultures of Mycoplasma arthritidis, a species which produces polyarthritis in rats.