The subcellular distribution of gold (sodium aurothiomalate) in monkey liver in vivo

R.W. Mason; E.G. McQueen; R.P. Sharma

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The subcellular distribution of gold (sodium aurothiomalate) in monkey liver in vivo

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The subcellular distribution of gold (sodium aurothiomalate) in monkey liver in vivo

R.W. Mason, E.G. McQueen and R.P. Sharma

Proceedings of the University of Otago Medical School, Vol.55(1), pp.13-14

Proceedings of the University of Otago Medical School

1977

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https://hdl.handle.net/10523/13119

Abstract

aurothiomalate sodium au 195

radioisotope

unclassified drug

cytosol

drug distribution

liver

liver cell

liver homogenate

lysosome

microsome

mitochondrion

monkey

theoretical study

Sodium aurothiomalate is used in the therapy of rheumatoid arthritis. Studies by others on the subcellular distribution of aurothiomalate in rats have suggested a possible association of gold with lysosomes. In the present experiments the subcellular distribution of gold in the livers of rhesus monkeys was studied at different intervals after the animals had been given [195Au]aurothiomalate.

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Record Identifier: 9926479933001891
Title: The subcellular distribution of gold (sodium aurothiomalate) in monkey liver in vivo
Creators: R.W. Mason
E.G. McQueen
R.P. Sharma
Publication Details: Proceedings of the University of Otago Medical School, Vol.55(1), pp.13-14
Academic Unit: Otago Medical School Research Society
Publisher: Otago Medical School Research Society
Date published ; e-published: 1977
Date copyright: 1977
Comment: Abstract presented at Otago Medical Research Society meeting. There is no published article available. If abstract text is digitally available, it will be included in this record. This item is available in holdings at University of Otago Libraries. See https://otago.primo.exlibrisgroup.com/permalink/64OTAGO_INST/qef3lj/alma9911647701891 for more information.
Language: English
Resource Type; Subtype: Conference proceeding

The subcellular distribution of gold (sodium aurothiomalate) in monkey liver in vivo

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