6/9/25 We are currently making changes to reflect the new Health Sciences Division structure. Thank you for your patience.

Sign in
Back
A high-throughput screening assay for identification of inhibitors of the A(1)A(O)-ATP synthase of the rumen methanogen Methanobrevibacter ruminantium M1
Journal article   Peer reviewed

A high-throughput screening assay for identification of inhibitors of the A(1)A(O)-ATP synthase of the rumen methanogen Methanobrevibacter ruminantium M1

Htin Lin Aung, Debjit Dey, Peter H. Janssen, Ron S. Ronimus and Gregory M. Cook
Journal of microbiological methods, Vol.110, pp.15-17
01/03/2015
DOI: https://doi.org/10.1016/j.mimet.2014.12.022
Handle:
https://hdl.handle.net/10523/36536

Abstract

Biochemical Research Methods Biochemistry & Molecular Biology Life Sciences & Biomedicine Microbiology Science & Technology
We report the development of a high-throughput screening platform to identify inhibitors of the membrane-bound A(1)A(O)-ATP synthase from the rumen methanogen Methanobrevibacter ruminantium Ml. Inhibitors identified in the screen were tested against growing cultures of M. ruminantium, validating the approach to identify new inhibitors of methanogens. (C) 2015 Elsevier B.V. All rights reserved.

Metrics

11 Record Views
4 Times Cited - Web of Science

Details

Logo image