An IL-6-IL-8 score derived from principal component analysis is predictive of adverse outcome in acute myocardial infarction

Gisela A. Kristono; Ana S. Holley; Kathryn E. Hally; Morgane M. Brunton-O'Sullivan; Bijia Shi; Scott A. Harding; Peter D. Larsen

doi:10.1016/j.cytox.2020.100037

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An IL-6-IL-8 score derived from principal component analysis is predictive of adverse outcome in acute myocardial infarction

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An IL-6-IL-8 score derived from principal component analysis is predictive of adverse outcome in acute myocardial infarction

Gisela A. Kristono, Ana S. Holley, Kathryn E. Hally, Morgane M. Brunton-O'Sullivan, Bijia Shi, Scott A. Harding and Peter D. Larsen

Cytokine: X, Vol.2(4), pp.100037-100037

01/12/2020

DOI: https://doi.org/10.1016/j.cytox.2020.100037

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https://hdl.handle.net/10523/19874

Abstract

• Principal component analysis (PCA) can create scores from collinear markers. • This study shows a PCA-derived score can combine cytokines in AMI patients. • An IL-6-IL-8 score using PCA independently predicts poor outcomes in AMI.

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Record Identifier: 9926495108201891
Title: An IL-6-IL-8 score derived from principal component analysis is predictive of adverse outcome in acute myocardial infarction
Creators: Gisela A. Kristono
Ana S. Holley
Kathryn E. Hally
Morgane M. Brunton-O'Sullivan
Bijia Shi
Scott A. Harding
Peter D. Larsen
Publication Details: Cytokine: X, Vol.2(4), pp.100037-100037
Academic Unit: Surgery and Critical Care (UOW); Medicine (UOW)
Publisher: Elsevier
Date published ; e-published: 01/12/2020
Language: English
Resource Type ; Subtype: Journal article