Anti-CRISPRs deconstruct bacterial defense

Nils Birkholz; Peter C. Fineran

doi:10.1016/j.molcel.2024.08.008

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Anti-CRISPRs deconstruct bacterial defense

Journal article

Peer reviewed

Anti-CRISPRs deconstruct bacterial defense

Nils Birkholz and Peter C. Fineran

Molecular cell, Vol.84(17), pp.3172-3174

05/09/2024

DOI: https://doi.org/10.1016/j.molcel.2024.08.008

Handle:

https://hdl.handle.net/10523/41985

Abstract

CRISPR-Cas

bacterial defense

anti-CRISPR mechanism

Deploying anti-CRISPR proteins is a potent strategy used by phages to inhibit bacterial CRISPR-Cas defense. In a new Nature paper, Trost et al.1 discover and characterize an exciting anti-CRISPR mechanism with possible implications beyond this microscopic arms race.

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Record Identifier: 9926563079901891
Title: Anti-CRISPRs deconstruct bacterial defense
Creators: Nils Birkholz
Peter C. Fineran
Publication Details: Molecular cell, Vol.84(17), pp.3172-3174
Academic Unit: Microbiology and Immunology; Genetics Otago
Publisher: Elsevier Inc
Grant note: Research in the Phage-Host Interactions Lab is funded by the Marsden Fund (Royal Society of New Zealand [RSNZ] Te Apārangi), Bioprotection Aotearoa, and the New Zealand Ministry of Business, Innovation & Employment (MBIE) Hīkina Whakatutuki. N.B. is supported by a Career Development Postdoctoral Fellowship by the Division of Health Sciences, University of Otago; P.C.F. is supported by a James Cook Research Fellowship (RSNZ).
Date published ; e-published: 05/09/2024
Language: English
Resource Type ; Subtype: Journal article