Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic

Natalie Lorenz; Alex James; Tiaan Van Rooyen; Aimee Paterson; Ciara Ramiah; Lauren Carlton; Prachi Sharma; Michael G Baker; Richard Charlewood; Reuben McGregor; Nicole J Moreland

doi:10.1093/infdis/jiae611

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Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic

Journal article

Open access

Peer reviewed

Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic

Natalie Lorenz, Alex James, Tiaan Van Rooyen, Aimee Paterson, Ciara Ramiah, Lauren Carlton, Prachi Sharma, Michael G Baker, Richard Charlewood, Reuben McGregor, …

The Journal of infectious diseases, jiae611

14/12/2024

DOI: https://doi.org/10.1093/infdis/jiae611

Handle:

https://hdl.handle.net/10523/44302

Abstract

Group A Streptococcus

Sars-CoV-2

antibody

immunity

respiratory syncytial virus

waning

Surges in infections caused by respiratory pathogens have been documented in multiple settings after relaxation of pandemic restrictions. Antibodies to major antigens from respiratory syncytial virus and Group A Streptococcus waned significantly in a longitudinal adult cohort throughout the pandemic. This waning may have contributed to the pathogen-surges that followed.Surges in infections caused by respiratory pathogens have been documented in multiple settings after relaxation of pandemic restrictions. Antibodies to major antigens from respiratory syncytial virus and Group A Streptococcus waned significantly in a longitudinal adult cohort throughout the pandemic. This waning may have contributed to the pathogen-surges that followed.

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Details

Record Identifier: 9926664806401891
Title: Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic
Creators: Natalie Lorenz
Alex James
Tiaan Van Rooyen
Aimee Paterson
Ciara Ramiah
Lauren Carlton
Prachi Sharma
Michael G Baker
Richard Charlewood
Reuben McGregor
Nicole J Moreland
Publication Details: The Journal of infectious diseases, jiae611
Academic Unit: Public Health (UOW)
Publisher: Oxford University Press
Grant note: This work was supported by funding from the Maurice Wilkins Centre for Biodiscovery. TVR was supported by a University of Auckland Research Masters Scholarship.
Date published ; e-published: 14/12/2024
Language: English
Resource Type ; Subtype: Journal article