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Evaluation of Acute and Convalescent Antibody Concentration Against Pneumococcal Capsular Polysaccharides for the Diagnosis of Pneumococcal Infection in Children with Community-Acquired Pneumonia
Journal article   Open access   Peer reviewed

Evaluation of Acute and Convalescent Antibody Concentration Against Pneumococcal Capsular Polysaccharides for the Diagnosis of Pneumococcal Infection in Children with Community-Acquired Pneumonia

Michael J. Carter, Sonu Shrestha, Peter O’Reilly, Pallavi Gurung, Meeru Gurung, Stephen Thorson, Rama Kandasamy, Merryn Voysey, Elizabeth O’Mahony, Sarah Kelly, …
The Pediatric infectious disease journal, Vol.43(2), pp.e67-e70
01/02/2024
DOI: https://doi.org/10.1097/INF.0000000000004185
Handle:
https://hdl.handle.net/10523/23068

Abstract

Brief Reports
We evaluated whether the quantification of IgG to pneumococcal capsular polysaccharides is an accurate diagnostic test for pneumococcal infection in children with pneumonia in Nepal. Children with pneumococcal pneumonia did not have higher convalescent, or higher fold change, IgG to pneumococcal polysaccharides than children with other causes of pneumonia. Caution is needed in interpreting antibody responses in pneumococcal infections.
url
https://doi.org/10.1097/INF.0000000000004185View
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