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Geographical variability in dabigatran dosing within New Zealand
Journal article   Open access   Peer reviewed

Geographical variability in dabigatran dosing within New Zealand

Liam T. Berryman, Paul K. L. Chin, Lorna J. Pairman, Milan Sundermann and Matthew Doogue
Internal medicine journal
25/05/2026
Handle:
https://hdl.handle.net/10523/51134

Abstract

New Zealand anticoagulant dabigatran pharmacology therapeutic drug monitoring
Dabigatran etexilate is an oral anticoagulant with increased risk of bleeding at high drug exposure. It is available in three capsule strengths (75, 110 and 150 mg). We analysed New Zealand dispensing data from 2019 to 2023 to compare use between health districts. Overall use was similar across districts. Canterbury had the highest 75 mg use (22.2 vs 1.6–7.6 people per 10 000 in the other districts). This relates to differences in local guidelines, therapeutic drug monitoring and availability of clinical pharmacology services. It is unknown if there are differences in patient outcomes.
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Internal Medicine Journal - 2026 - Berryman - Geographical variability in dabigatran dosing within New Zealand632.05 kBDownloadView
Published (Version of record) Open Access CC BY-NC V4.0
url
https://doi.org/10.1111/imj.70477View
Published (Version of record) Open CC BY-NC V4.0

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