Large Reductions in Invasive Pneumococcal Disease and Related Morbidities Among Children in New Zealand After Change from PCV10 to PCV13

Andrew Anglemyer; Anushka Srinivas; Andrea McNeill; Charlotte Allen; Hannah Cooper; Julie Morgan; Xiaoyun Ren; Kara DuBray; Alexander Humphrey; Emma Best; Matthew Parry; Tony Walls

doi:10.1093/infdis/jiaf587

Back

Large Reductions in Invasive Pneumococcal Disease and Related Morbidities Among Children in New Zealand After Change from PCV10 to PCV13

Journal article

Peer reviewed

Large Reductions in Invasive Pneumococcal Disease and Related Morbidities Among Children in New Zealand After Change from PCV10 to PCV13

Andrew Anglemyer, Anushka Srinivas, Andrea McNeill, Charlotte Allen, Hannah Cooper, Julie Morgan, Xiaoyun Ren, Kara DuBray, Alexander Humphrey, Emma Best, …

The Journal of infectious diseases, jiaf587

20/11/2025

DOI: https://doi.org/10.1093/infdis/jiaf587

Handle:

https://hdl.handle.net/10523/48891

Abstract

vaccine preventable diseases

serotypes

pneumococcal disease

pneumococcal conjugate vaccine

Purpose: In New Zealand after multiple changes to the immunization program, PCV13 was re-introduced in 2022, replacing PCV10. We investigate the resultant epidemiology of this change. Methods: Using invasive pneumococcal disease (IPD) surveillance data, we compared incidence rates in different PCV eras and predicted the number of pediatric cases we would have expected, assuming PCV10 was still part of the immunization program. Results: IPD incidence among children has decreased. Without a vaccine change, incidence was predicted to continue increasing, driven by serotype 19A. Conclusions: The timely change in pneumococcal vaccine and subsequent incidence decreases underscores the importance of epidemiology-driven decisions.

Metrics

4 Record Views

See more details

Details

Record Identifier: 9926793259601891
Title: Large Reductions in Invasive Pneumococcal Disease and Related Morbidities Among Children in New Zealand After Change from PCV10 to PCV13
Creators: Andrew Anglemyer
Anushka Srinivas
Andrea McNeill
Charlotte Allen
Hannah Cooper
Julie Morgan
Xiaoyun Ren
Kara DuBray
Alexander Humphrey
Emma Best
Matthew Parry
Tony Walls
Publication Details: The Journal of infectious diseases, jiaf587
Academic Unit: Mathematics and Statistics; Paediatrics and Child Health (UOC); Public Health (DSM); Statistics
Publisher: Oxford University Press
Grant note: New Zealand Ministry of Health
Date published ; e-published: 20/11/2025
Comment: The published version is not available in full-text in OUR Archive. Where available, a link to the published version is provided (check the DOI and/or the Files and links section). The full-text item may be open access on the publisher's website. An earlier version of the work (such as authors' accepted manuscript following peer-review or unreviewed preprint/author's original version) may be available in the Files and links section of this record. Alternatively, readers may have subscription access to the full-text from the publisher.
Language: English
Resource Type ; Subtype: Journal article

Large Reductions in Invasive Pneumococcal Disease and Related Morbidities Among Children in New Zealand After Change from PCV10 to PCV13

Abstract

Related links

Metrics

Details