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Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
Journal article   Open access

Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets

Matthias Fellner
ADMET & DMPK, Vol.10(2), pp.107-114
01/01/2022
Handle:
https://hdl.handle.net/10523/37409

Abstract

Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology
There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development. (C) 2021 by the authors.
url
https://doi.org/10.5599/admet.1137View
Published (Version of record) Open

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