Point-of-Care High-Sensitivity Troponin Use in an ESC-Type Pathway for Assessment of Possible Acute Myocardial Infarction in the Emergency Department

Logan Fann; Laura R Joyce; John W Pickering; Andrew Munro; Nick Fisher; Martin Than

doi:10.1111/1742-6723.70147

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Point-of-Care High-Sensitivity Troponin Use in an ESC-Type Pathway for Assessment of Possible Acute Myocardial Infarction in the Emergency Department

Journal article

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Point-of-Care High-Sensitivity Troponin Use in an ESC-Type Pathway for Assessment of Possible Acute Myocardial Infarction in the Emergency Department

Logan Fann, Laura R Joyce, John W Pickering, Andrew Munro, Nick Fisher and Martin Than

Emergency medicine Australasia, Vol.37(5), e70147

12/10/2025

DOI: https://doi.org/10.1111/1742-6723.70147

Handle:

https://hdl.handle.net/10523/48364

Abstract

chest pain

emergency department

myocardial infarction

point‐of‐care

troponin

This prospective observational study aimed to assess the diagnostic utility of point-of-care (POC) high-sensitivity troponin (hs-cTn) within an ED chest pain pathway. Patients had paired laboratory hs-cTnT and POC hs-cTnI on arrival. Clinical care utilised the hs-cTnT result. Allocation to risk classes was compared between hs-cTnT and POC hs-cTnI. AMI was adjudicated blinded to the POC result. Of 184 patients, 14 (7.6%) had AMI. Twenty-one (11.4%) had AMI ruled out by hs-cTnT and 59 (32.1%) by POC, both with 100% sensitivity. The POC test returned invalid results in 17 patients (8.5%). A POC hs-cTnI assay within a clinical pathway may effectively risk stratify for AMI.

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Record Identifier: 9926779596501891
Title: Point-of-Care High-Sensitivity Troponin Use in an ESC-Type Pathway for Assessment of Possible Acute Myocardial Infarction in the Emergency Department
Creators: Logan Fann
Laura R Joyce
John W Pickering
Andrew Munro
Nick Fisher
Martin Than
Publication Details: Emergency medicine Australasia, Vol.37(5), e70147
Academic Unit: Surgery and Critical Care (UOC); Medicine (UOC)
Publisher: Wiley
Grant note: Canterbury Medical Research Foundation; Siemens Healthineers; 19/234 / Health Research Council of New Zealand
Date published ; e-published: 12/10/2025
Comment: The published version is not available in full-text in OUR Archive. Where available, a link to the published version is provided (check the DOI and/or the Files and links section). The full-text item may be open access on the publisher's website. An earlier version of the work (such as authors' accepted manuscript following peer-review or unreviewed preprint/author's original version) may be available in the Files and links section of this record. Alternatively, readers may have subscription access to the full-text from the publisher.
Language: English
Resource Type ; Subtype: Journal article

Point-of-Care High-Sensitivity Troponin Use in an ESC-Type Pathway for Assessment of Possible Acute Myocardial Infarction in the Emergency Department

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