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STDP rule endowed with the BCM sliding threshold accounts for hippocampal heterosynaptic plasticity
Journal article   Peer reviewed

STDP rule endowed with the BCM sliding threshold accounts for hippocampal heterosynaptic plasticity

Lubica Benuskova and Wickliffe C Abraham
Journal of computational neuroscience, Vol.22(2), pp.129-133
01/04/2007

Abstract

Action Potentials - physiology Animals Dentate Gyrus - cytology Models, Neurological Neuronal Plasticity - physiology Neurons - physiology Synapses - physiology Time Factors
We have combined the nearest neighbour additive spike-timing-dependent plasticity (STDP) rule with the Bienenstock, Cooper and Munro (BCM) sliding modification threshold in a computational model of heterosynaptic plasticity in the hippocampal dentate gyrus. As a result we can reproduce (1) homosynaptic long-term potentiation of the tetanized input, and (2) heterosynaptic long-term depression of the untetanized input, as observed in real experiments.

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