The effect of d-cycloserine on brain processing of breathlessness over pulmonary rehabilitation: an experimental medicine study

Sarah L. Finnegan; Olivia K. Harrison; Sara Booth; Andrea Dennis; Martyn Ezra; Catherine J. Harmer; Mari Herigstad; Bryan Guillaume; Thomas E. Nichols; Najib M. Rahman; Andrea Reinecke; Olivier Renaud; Kyle T.S. Pattinson

doi:10.1183/23120541.00479-2022

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The effect of d-cycloserine on brain processing of breathlessness over pulmonary rehabilitation: an experimental medicine study

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The effect of d-cycloserine on brain processing of breathlessness over pulmonary rehabilitation: an experimental medicine study

Sarah L. Finnegan, Olivia K. Harrison, Sara Booth, Andrea Dennis, Martyn Ezra, Catherine J. Harmer, Mari Herigstad, Bryan Guillaume, Thomas E. Nichols, Najib M. Rahman, …

ERJ open research, Vol.9(2), p.479

01/03/2023

DOI: https://doi.org/10.1183/23120541.00479-2022

Abstract

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Although increasing evidence supports therapeutic modulation of NMDA pathways to treat symptoms of breathlessness in COPD, d -cycloserine does not demonstrate sufficient efficacy to be considered for phase 3 trials in pulmonary rehabilitation https://bit.ly/3Wm64ni

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Record Identifier: 9926514727601891
Title: The effect of d-cycloserine on brain processing of breathlessness over pulmonary rehabilitation: an experimental medicine study
Alternative title: d-cycloserine's effect on breathlessness brain processes
Creators: Sarah L. Finnegan
Olivia K. Harrison
Sara Booth
Andrea Dennis
Martyn Ezra
Catherine J. Harmer
Mari Herigstad
Bryan Guillaume
Thomas E. Nichols
Najib M. Rahman
Andrea Reinecke
Olivier Renaud
Kyle T.S. Pattinson
Publication Details: ERJ open research, Vol.9(2), p.479
Academic Unit: Psychology
Publisher: European Respiratory Society
Grant note: Grant RCF18/002 / ; Grant R333/0214 / ; 203139/Z/16/Z / ;
Date published ; e-published: 01/03/2023
Language: English
Resource Type: Journal article

The effect of d-cycloserine on brain processing of breathlessness over pulmonary rehabilitation: an experimental medicine study

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