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Use of ethanol locks to prevent recurrent central line sepsis
Journal article   Peer reviewed

Use of ethanol locks to prevent recurrent central line sepsis

Sarah C L Metcalf, Stephen T Chambers and Alan D Pithie
The Journal of infection, Vol.49(1), pp.20-22
01/07/2004
DOI: https://doi.org/10.1016/j.jinf.2003.08.010
Handle:
https://hdl.handle.net/10523/36387

Abstract

Adult Anti-Infective Agents, Local - administration & dosage Bacteremia - prevention & control Catheterization, Central Venous - adverse effects Equipment Contamination - prevention & control Ethanol - administration & dosage Humans Male Parenteral Nutrition, Total - instrumentation
Catheter-related sepsis (CRS) is a common complication of long-term parenteral nutrition. Conventional antibiotic therapy is often effective in the short-term but, because of poor activity against intraluminal microbial biofilms, may not prevent relapse. Ethanol is an effective antiseptic. We describe a case of a patient with recurrent CRS successfully treated with 70% ethanol locks.

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