Abstract
The full text of this article is freely and openly accessible from the following repository: https://europepmc.org/articles/pmc2249168
Objective: To describe the prevalence and associations of xerostomia among adults in their early thirties, with particular attention to medication exposure as a putative risk factor.
Material and Methods: The prevalence and associations of xerostomia were investigated among 32-year-old participants in a long-standing prospective cohort study. Some 950 individuals were assessed at ages 26 and 32 years, with medications being recorded on both occasions.
Results: The prevalence of xerostomia was 10.0% (with no apparent gender difference), and was significantly higher among those taking antidepressants (odds ratio/4.7), iron supplements (OR/4.1) or narcotic analgesics (OR/2.4). Those taking antidepressants at both ages 26 and 32 years had 22 times the odds of reporting xerostomia.
Conclusion: Xerostomia may be a problem for a sizeable minority of young adults.