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dc.contributor.advisorMoratti, Stephen C.
dc.contributor.advisorHanton, Lyall R.
dc.contributor.authorSantoso, Bagus
dc.date.available2020-05-20T00:38:56Z
dc.date.copyright2020
dc.identifier.citationSantoso, B. (2020). Thermoreversible hydrogels based on PEO stars (Thesis, Doctor of Philosophy). University of Otago. Retrieved from http://hdl.handle.net/10523/10074en
dc.identifier.urihttp://hdl.handle.net/10523/10074
dc.description.abstractThe aim of the project is to develop a range of hydrogels made from biocompatible monomers which could be used in various biomedical applications. The particular interest is on star-shaped block copolymers which consist of a hydrophilic core and a thermoresponsive arm. When heated above its LCST the thermoresponsive block aggregates and forms a physical cross-linking which is reversible upon cooling. In particular, the project will be focussing on gels that might be useful in tissue printing. In these methods, cells are deposited in a gel or gel precursor, the gel cross-linked, usually by UV, and placed in a growth media. Thermoresponsive gels seem ideally suited for this, as the lack of permanent cross-links might allow for easier cell growth and UV light can damage cells. In this work, commercial PEO stars will be used as the hydrophilic core and various thermoresponsive polymers were grown from it by ATRP.
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.publisherUniversity of Otago
dc.rightsAll items in OUR Archive are provided for private study and research purposes and are protected by copyright with all rights reserved unless otherwise indicated.
dc.subjectPolymer
dc.subjectChemistry
dc.subjectHydrogel
dc.subjectATRP
dc.subjectThermoresponsive
dc.subjectPEO
dc.subjectPEG
dc.subjectstar polymer
dc.subjectpoly(ethylene glycol)
dc.titleThermoreversible hydrogels based on PEO stars
dc.typeThesis
dc.date.updated2020-05-19T23:07:27Z
dc.language.rfc3066en
thesis.degree.disciplineChemistry
thesis.degree.nameDoctor of Philosophy
thesis.degree.grantorUniversity of Otago
thesis.degree.levelDoctoral
otago.interloanno
otago.openaccessOpen
otago.evidence.presentYes
otago.abstractonly.term26w
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