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Functional Analyses of the Neuropeptide FF Receptor System Using GJ14, a Potent and Selective Antagonist
The G-protein coupled neuropeptide FF receptors (NPFFR1 and NPFFR2) belong to the RFamide receptor subfamily. Of these, NPFFR1 is the most widespread and highly expressed receptor in the brain. The endogenous agonist ...
The Overlap of Hyperventilation Syndrome with Asthma and Anxiety
Hyperventilation Syndrome (HVS) is a functional breathing disorder characterised by recurrent or chronic changes in breathing pattern causing respiratory and non-respiratory complaints that cannot be attributed to any ...
Mapping Perspectives on an Ethically Challenging Paediatric Case
Objectives
This project aims to identify and examine in detail some of the ethically challenging aspects of the care of infants who have serious medical conditions, by looking at a multidisciplinary team (MDT) and whãnau ...
Lapita Plants, People and Pigs
The Lapita cultural complex is associated with the Austronesian expansion out of Island Southeast Asia beginning approximately 3,500 BP. Sites associated with this archaeological culture have been found from the coast of ...
Biomarkers of Kidney Function; Validity of Estimates in Clinical Practice
Chronic kidney disease (CKD) and acute kidney injury (AKI) are two common conditions that are encountered by clinicians, yet unlike the cardiac troponins, there is currently no gold-standard biomarker that can accurately ...
Corporate Social Responsibility and Tourism: Meaning, motivations and barriers in the Tanzanian tourism industry
This thesis explores how the notion of responsible business practice unfolds in a developing country context, Tanzania. The research provides important insights into how the socio-cultural environment shapes the uptake and ...
beta1- and beta2-adrenoceptor cardiovascular responsiveness in the type II Zucker Diabetic Fatty rat model
Sympathetic nervous system dysfunction is prevalent in diabetes. It is characterised by increased sympathetic nerve activity and elevated circulating catecholamine levels and altered β-adrenoceptor (β-AR) responsiveness. ...
Investigations into a cytochrome c variant that causes thrombocytopenia
Thrombocytopenia Cargeeg is a rare autosomal dominant disorder identified in a New Zealand family with low platelet counts. It is caused by a heterozygous mutation (G41S) in the CYCS gene, which encodes for cytochrome c ...
Deception: How do we feel about it, and how do we detect it?
The subjective experience of lying has been broadly theorized in deception research, with preference to the idea that humans feel either fear, guilt, or excitement (Ekman, 1985). Moreover, some authors suggest that ...
Thyroglobulin as a biomarker of iodine status
New Zealand (NZ) soils are low in iodine and consequently NZ has a history of iodine deficiency. Mild iodine deficiency has a number of adverse consequences including impaired cognition in children and an increased risk ...