Thesis - Doctoral
Recent Deposits
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pH responsive nanoparticles as versatile carriers for cancer chemotherapy and vaccination
Cancer is one of the leading causes of mortality and morbidity in the Western world. The anguish caused by cancer is exacerbated by current chemotherapeutic treatments as severe adverse effects can be caused by off-target ... -
Bending Form: Dynamic Content Within a Framework and the Recordings of the Beatles in the Mid-Sixties
This written exegesis, alongside three recorded albums, Pictures of Everyday, Baby Astronaut, and The Dunedin Electric Co., works to reconcile the analytic with implementation through a practice-as-research approach. The ... -
Development of fluorescent ligands for A1 adenosine receptor and cannabinoid receptors
Adenosine A1 receptor (A1AR), cannabinoid type 1 receptor (CB1R) and cannabinoid type 2 receptor (CB2R) are class A G protein-coupled receptors (GPCRs) and play important roles in human pathophysiological conditions such ... -
The comparative assessment of patient safety at hospitals in New Zealand
Patient safety is the avoidance, prevention and amelioration of adverse outcomes or injuries stemming from the healthcare system. Patient safety is the most important constituent of quality and has become increasing important ... -
Hop aroma in beer - changes in the flavour profile associated with different yeast strains and fermentation parameters
Beer has a complex flavour profile made up of hundreds of compounds, derived from its ingredients and changes that occur during the production process. Although beer flavour has been extensively researched, some of the ... -
Surface modified cubosomes for drug delivery across the blood-brain barrier
The bottleneck in delivering drugs to the brain for treatment of diseases related to central nervous system (CNS), lies behind the presence of blood-brain barrier (BBB). This barrier prevents most of the large and a number ... -
Place-Responsive Outdoor Education Pedagogy in Singapore Secondary Schools: A Case Study
Outdoor education in Singapore is gaining traction with recent policy changes emanating from the Government’s National Outdoor Education Masterplan. Concerningly, a lack of critical examination and review of the policy ... -
Māori Women Promoting Food Sovereignty in Aotearoa (New Zealand)
Poverty and food insecurity are issues being felt in Māori communities. Food insecurity includes the malnutrition of essential nutrients due to the inadequate intake of fruits and vegetables, exacerbated by the widespread ... -
Quantitative Electroencephalogram Neuroimaging in Obesity
Efforts to understand and treat obesity come from a wide range of disciplines. Neuroimaging in obesity is typically performed with fMRI and PET, which are indirect measures of neural activity. EEG is a direct measure of ... -
Effect of high intensity interval training on the left ventricular performance in the type 2 diabetic heart
Early studies in the 1970s revealed the now well-established link between diabetes and cardiovascular disease, the main cause of death and disability among this cohort. It is believed that biochemical changes to the proteins ... -
Development and Applications of Stimuli-Responsive Drug Delivery Strategies
In this thesis, bioorthogonal chemistry was explored as a means of developing stimuli-responsive nanoparticles and hydrogels. It has been hypothesised that the use of stimuli-responsive drug delivery systems will improve ... -
A Regional and Nationwide Perspective on the Relationship between Sleep Disordered Breathing and Academic Performance in New Zealand Children
Objectives The main aims of this thesis were to: (i) investigate the concurrent associations between sleep disordered breathing (SDB), neurobehavioural, and academic performance at 8 years, (ii) determine the impact of ... -
The effect of co-creation through exposure to augmented reality on customer perceived risk, perceived trust and purchase intent
In recent years, due to advancements of technology, customers are empowered and better informed about the market (Prahalad & Ramaswamy, 2004b). Companies better understand that the balance of power has shifted and that ... -
Examining Traditional Maaori Knowledge Frameworks and Intergenerational Knowledge Transmission “Titiro, Whakarongo” - he huarahi ako noo ngaa raa o nehe. “Look, Listen”- a way of learning from days past.
Te Aria (Abstract) This thesis investigates the way knowledge is transmitted inter-generationally, and the teaching and learning methods (or pedagogies) used to do this. The transmission referred to here relates to knowledge ... -
New lamps for old : the activities of Sir Rex De Charembac Nan Kivell as a collector and dealer of fine art
Sir Rex Nan Kivell (1898-1977) was a New Zealand-born art dealer and collector, who was managing director of the Redfern Gallery in London's Mayfair from 1931 to 1965. His birth was illegitimate and the father is not known. ... -
Reversal theory and flow : toward an integrated framework of optimal experiences in adventure activities
Although adventurous pursuits are gaining popularity, many leading theoretical paradigms within the adventure literature (e.g., the Adventure Experience Paradigm) lack predictive power and depth. Flow Theory (Csikszentmihalyi, ... -
Handle with Care
This thesis is drawn from an empirical project that sought to better understand the work of clinician-patient relationships in psychiatry in a contemporary, mainstream Western societal context. The project was carried out ... -
The Economic Impact of Climate Change on Farm Decisions and Food Consumption in Ghana
Climate change poses a serious threat to the growth of developing countries, especially Ghana where the majority of people derive their livelihoods directly from agriculture and related industries. This thesis sets out to ... -
How can a contemporary composer use film to enhance music?
There is a body of literature on music in film, and some analytical writing on music video, but almost no writing that approaches the subject from the point of view of how the film might support the music. My research ... -
The effect of poverty on cognitive function: Does a reminder of financial hardship affect subsequent decision-making?
The conditions of poverty are thought to change the way people process information and make decisions. Past research has shown when low-income participants are reminded of their financial situation they perform worse on ...