Abstract
The rapid expansion of demand for fish supplies for human consumption has led to the exhaustion of many marine fisheries. Any further increment to satisfy this demand must come from the aquaculture industry. To successfully breed fish in captivity, however, the synchronisation of reproduction must be achieved. Presently, this predominantly involves the parenteral administration of gonadotropin-releasing hormone (GnRH). Because of the recognised disadvantages associated with this route, such as increased stress on fish, oral routes of delivery to fish including salmon are being attempted. However, little is still known of the intestinal barriers to oral peptide delivery in salmon. Therefore, this thesis investigated the physical barriers to oral peptide delivery to salmon and methods to improve such delivery. […]