School of Pharmacy
Recent Deposits
-
Spray-dried powder particles for treating pulmonary tuberculosis
Background Tuberculosis (TB) is a major global health burden. Rapid emergence of drug-resistant TB has aggravated the current situation of global TB. High dose delivery of drugs to the lung using a dry powder inhaler (DPI) ... -
Formulation Strategies to Enhance Nose-to-Brain Delivery of Drugs
Delivery of drugs via the intranasal olfactory route is a non-invasive and practical method of bypassing the blood-brain barrier (BBB). However, targeted delivery and retention of drugs to the olfactory region is a significant ... -
Spectroscopic investigation and quantitation of polymorphism and crystallinity of pharmaceutical compounds
Spectroscopy is increasingly used to investigate and monitor the solid state forms of pharmaceutical materials and products. Spectroscopy's speed, non-destructive sampling, compatibility with fibre optics and safety also ... -
Towards a deeper understanding of the polymorphic conversion of carbamazepine in aqueous suspension
Polymorphism can influence every aspect of the properties of a solid including the shelf life, dissolution rate, solubility, formulation properties and processing properties of a solid drug. A deeper understanding of ... -
Data Collected about Intentional Self-poisoning in New Zealand Emergency Departments and the Implications of Data Limitations for Prevention Planning
Background Intentional self-poisoning (ISP; taking a purposeful overdose) results in significant morbidity and is a burden on population health. In order to reduce ISP by, for example, restricting inappropriate access to ... -
Clinical decision-making: An essential skill for 21st century pharmacy pratice
Clinical decision-making skills are recognized as a central component of professional competency but are underdeveloped in pharmacy compared to other health professions. There is an urgent need for a comprehensive understanding ... -
Development of Fluorescent Ligands for CB2 receptor
CB2 receptor plays an important role in inflammation and has been implicated in the pathologies of several diseases, including neurodegenerative disorders, cancer, and atherosclerosis. However, there is a lack of understanding ... -
The Communication of Science through Crime Fiction
Background: Science can be communicated informally through fictional media. Crime fiction in print media has contained elements of forensic science since the first detective stories, for example, Sherlock Holmes. Modern ... -
Deprescribing in Older New Zealanders
Polypharmacy, the prescription of five or more medicines, is an emerging worldwide health concern. When older people are prescribed five or more medicines, they are susceptible to a wide variety of negative health consequences, ... -
The dose individualisation of oral anticoagulants
Oral anticoagulants are used to treat and prevent blood clots. All anticoagulants carry the risk of bleeding if the systemic exposure is too high, while inadequate exposure will increase the risk of thrombosis. Therefore, ... -
ISCOMs and related colloidal particles prepared by the lipid film hydration method for antigen delivery
Purposes: The aims of this thesis were to physicochemically investigate the formation of ISCOM matrices and other types of colloidal particles formed in aqueous dispersion as a function of different mass ratios of Quil A, ... -
The introduction of an advanced role for pharmacy technicians into the New Zealand pharmacy setting
The roles of pharmacists and pharmacy technicians are changing, both within New Zealand and internationally. The move of New Zealand pharmacists into the more clinically focused roles of their overseas colleagues has however ... -
What patients pay for medicines: a comparison of six countries
Introduction Pharmaceutical expenditure is rising in high-income countries. Some countries choose to pass some of these costs on to patients through various cost-sharing strategies. In many countries, patients pay an ... -
I can see clearly now: Survey results from neonatal staff on mydriatic use in retinopathy or prematurity screening
Aims: Very preterm infants require mydriatic eye drops in preparation for retinopathy of prematurity examination. Mydriatic dosing needs to provide adequate pupil dilation for the examination and yet, avoid adverse ... -
Lack of evidence and consequential harm caused by mydriatic regimens used in retinopathy of prematurity screening.
Approximately 3,500 infants in New Zealand and Australia are screened annually for retinopathy of prematurity (ROP). To view the retina and diagnose ROP, adequate pupil dilation with mydriatic medicines is required. ... -
Developing Novel Chlamydia-Targeted Protease Inhibitors
Chlamydia trachomatis is an obligate intracellular human parasite responsible for the most common sexually transmitted bacterial infection world-wide. The largely asymptomatic infection frequently results in complications ... -
Pharmacoepidemiological approaches examining preventive medicines and multimorbidity in older people
Prescribing medicines for older people, aged 65 years and older, with multimorbidity is challenging. Preventive medicines are often prescribed in older people to prevent diseases or to confer health benefits. However, it ... -
Maternity Outcomes and Access following Regulatory Changes for Isotretinoin Prescribing in New Zealand
Aims: Oral isotretinoin is an effective treatment for severe acne that is teratogenic. On 1 March 2009 funded access to oral isotretinoin in New Zealand was extended from dermatologist-only to also include prescriptions ... -
Psychotropic medicine utilisation in older people: A pharmacoepidemiological approach
Psychotropic medicines are defined by World Health Organisation Collaborating Centre for Drug statistics Methodology as psycholeptics (central nervous system calming effect) and psychoanaleptics (central nervous system ... -
Factors affecting glucose homeostasis in premature neonates
Introduction After birth rapid metabolic adaptation is required to establish glucose homeostasis.Preterm birth disrupts normal timing of this physiological adaptation putting premature neonates at risk of hypo- and ...