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The aetiology of febrile illness in low-and-middle income countries
Fever is a common reason for people to seek healthcare in low-and-middle-income countries. For decades, cases of febrile illness have often been considered to be malaria and treated as such. However, with apparent declines ...
Sildenafil in the treatment of fat embolism: a rat model
ABSTRACT
Background: Sudden, peri-operative cardiovascular deterioration with decreased systemic arterial pressure and increased pulmonary arterial pressure is a potentially fatal complication ...
Multiple Dosing of RHDV VLP to Enhance the Anti-tumour Response
Metastatic melanoma has a poor prognosis, with a median survival of 13 months after diagnosis. New Zealand has among the highest melanoma rates in the world with more than 2000 cases registered every year. Metastatic ...
Sleep and the potential of sleep hygiene for weight management in youth
The rate and prevalence of childhood obesity and its associated morbidities, such as obstructive sleep apnoea (OSA), is increasing. Sleep disruption due to OSA has been associated with neurobehavioural impairments such as ...
Edible Gardens in New Zealand Schools
The epidemiological transition has seen Public Health shift its focus from communicable diseases to non-communicable diseases; national health systems are realigning their priorities to combat the rise of chronic disease. ...
Investigation of a mutation in CYP26B1
Retinoic acid is known to have several important roles in embryonic development, including limb and hindbrain development and has been shown to induce neural tube defects when it is present at teratogenic levels. The CYP26 ...
Chronic Kidney Disease and its Clinical Implications on Red Blood Cell Survival and Glycaemic Control
World-wide the incidence of individuals developing stage 3 to stage 5 chronic kidney disease (CKD) is increasing. Diabetic nephropathy is the major aetiological factor for this increasing epidemic of CKD. A significant ...
The Genetic and Biological Characterisation of Complex Skeletal Diseases
Understanding the aetiology of genetic diseases is important for furthering the fields of genetics, biochemistry and medicine. This project utilises microarray and Next Generation Sequencing technology to elucidate the ...
Identifying Inflammatory Markers in Vascular Disease
Introduction: Cardiovascular disease remains the leading cause of death and disability globally. There has been much interest into the role that inflammation plays in the pathogenesis of cardiovascular disease. The ...
Stress Conditioning for Peripheral Arterial Disease
Exercise is important for maintaining health, and for the prevention and treatment of many cardiovascular diseases. Unfortunately, some individuals face significant barriers to exercise. Patients with peripheral arterial ...