School of Biomedical Sciences
Sub-communities within School of Biomedical Sciences
Collections in School of Biomedical Sciences
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Anatomy [180]
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Physiology [98]
Recent Deposits
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Evaluating environmental DNA (eDNA) metabarcoding as a method for monitoring biodiversity in marine ecosystems.
Halting current global biodiversity loss is important to maintain ecosystem functioning. To succeed in halting biodiversity loss, information is needed on community composition, abundance of species, and changes in these ... -
Investigating cellular remodelling events induced by the oncolytic Seneca Valley Virus
Cancer is a worldwide problem affecting millions of people. Typical cancer treatments are often very toxic and have a range of negative side effects. A new field of cancer research that may provide new cancer therapies is ... -
Quantifying global CG methylation in regenerative Zebrafish caudal fin and Xenopus tail buds.
Epigenetics is a control mechanism that creates stable alterations in gene expression thatdoes not require underlying changes in DNA sequence. One of the most iconic and prevalent epigenetic mechanisms involves CG methylation, ... -
An investigation in the neuromodulation of olfactory function using non-invasive vagus nerve stimulation
In the existing literature, invasive direct vagus nerve stimulation (VNS) using high frequencies has shown to be effective in modulating the activity of the olfactory bulb in animal models. Under indirect vagus nerve ... -
Nutritional Factors in the Paleoepidemiology of Infectious Disease in the Ancient Atacama Desert
The adoption of agriculture in ancient human groups is thought to have resulted in a general decline in health, as evidenced by an increase in skeletal markers of infectious disease and nutritional stress in post-transitional ... -
Association of Polynesian-specific variants of PRPSAP1 and SLC22A3 genes with gout.
Gout is a complex disease caused by over-production and/or under-excretion of urate, which causes hyperuricaemia. This leads to urate deposition, and initiates the formation of monosodium urate (MSU) crystals in joints and ... -
Characterisation of Plant Cysteine Dioxygenase
Many organisms possess a non-heme, mononuclear iron enzyme termed cysteine dioxygenase (CDO) that aids in homeostasis. This enzyme irreversibly adds molecular oxygen to the thiol group of the N-terminal cysteine residue ... -
Engineering quorum-quenching enzymes
Biofilms are structured communities of bacteria that adhere to surfaces and shield bacteria from hostile surroundings. They are implicated in 75% of all infections in humans and are difficult to treat. New therapies are ... -
Genetic Determinants of Host-Specificity in Mesorhizobium loti NZP2037
The establishment of a successful symbiotic interaction between rhizobia and their respective legume hosts involves complex molecular interactions between the two prospective partners. The determinants behind the specificity ... -
Functional analysis of poxvirus anaphase-promoting complex regulator (PACR), an orf virus cell cycle regulator.
Viruses, after long periods of time infecting and co-evolving with their hosts have developed complex and ingenious ways of manipulating host cell environments to better suit their needs. One such example of this is ... -
Controlled Delivery of Nitric Oxide Using Stable and Stimuli-Responsive S-nitrosothiols
Nitric oxide (NO) is a short-lived, endogenously produced gas which plays multiple roles in mammalian physiology. A broad range of NO donors has emerged as potential therapeutics in different pathological processes including ... -
Temporal Effects of Acoustic Trauma-Induced Tinnitus on the Extracellular Levels of Amino Acids in the Inferior Colliculus of Rats.
Tinnitus is often defined as the perception of sound in the absence of a physical or an external acoustic source. While the exact underlying causes of tinnitus remain poorly understood, there is growing evidence to suggest ... -
Neuronal activity in the striatum in response to vestibular stimulation
There has been speculation into connections between the basal ganglia and the vestibular system for the last century. However, the results of studies investigating these connections have been inconsistent and controversial. ... -
Combination of Cardiac Progenitor Cells from the Right Atrium and Left Ventricle provide Synergistic Paracrine Effects for In Vitro Cardiac Repair
Cardiovascular diseases, such as ischaemic heart disease, remain the most common cause of death worldwide. With no effective treatment to replace the loss of cardiac tissue following a myocardial infarction, ischaemic heart ... -
The effect of exercise on diabetic heart disease
The American Diabetes Association recommends either a moderate-intensity exercise (MIE) or high-intensity exercise (HIE) regime as part of the healthy lifestyle for diabetic individuals. However, it is not known what ... -
Ice activities in New Zealand Chionochloa species
Overwintering plants produce ice active agents with low thermal hysteresis but a higher ability to inhibit the recrystallization of ice crystals already formed. Many plants also minimize the damage from freezing by triggering ... -
Leptin and insulin signaling on midbrain dopamine neurons do not modulate anxiety and depression behaviours
Anxiety is a highly aroused negative emotional state that occurs in response to potential danger, and can be inappropriately intensified due to aberrations in the aversion pathway of mesocorticolimbic dopamine circuitry. ... -
Factors Affecting The Advancement Of Atherosclerotic Plaques
Cardiovascular disease (CVD) is the leading cause of death worldwide in adult men and women. Atherosclerotic cardiovascular disease (ASCVD) has been highlighted as the main cause of death among CVDs, due to development and ... -
Hybrid Assembly of the Chytrid Genome - Insights into the Evolution and Outbreak of a Major Amphibian Pathogen
Devastating amphibian population declines have been observed globally for the last 40 years. These declines have become the interest of several conservationists and researchers, as amphibians form a valuable part of global ... -
The regulation of ascorbate in apples (Malus domestica)
Ascorbate is an essential biochemical for biological processes in plants and animals. Ascorbate concentrations vary greatly between closely related species of plants, and can even differ across cultivars of the same species. ...