School of Biomedical Sciences
Sub-communities within School of Biomedical Sciences
Collections in School of Biomedical Sciences
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Anatomy [191]
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Physiology [120]
Recent Deposits
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Characterisation of genes involved in exopolysaccharide biosynthesis and transport in the Mesorhizobium loti strain R7A
Rhizobia are bacteria that are important in fixing gaseous nitrogen into a plant-available form via a symbiotic interaction with leguminous plants. In order for this to occur, the legume and the rhizobia must communicate ... -
Bioavailability and biological effects of isothiocyanates from broccoli sprout powder
Broccoli sprout powder (BSP) is a rich source of glucosinolates that can be hydrolysed to isothiocyanates by enzyme myrosinase when the powder comes into contact with water. The major isothiocyanate produced in broccoli ... -
Regulation of Corticotropin-Releasing Hormone Neuron Activity by Noradrenergic Stress Signals
The stress response is crucial for allowing adaptation to an ever-changing external environment. The neuroendocrine stress response is controlled by corticotropin-releasing hormone (CRH) neurons located within the ... -
Maternal obesity affects neurogenesis in the lateral hypothalamic area
Many human epidemiological studies have reported maternal obesity confers an increased risk for obesity and metabolic disorders within the offspring. Additionally this effect has been observed in numerous animal models of ... -
Transcriptomic and Proteomic Approaches to the Analyses of Orf Virus and its Ankyrin Repeat Proteins
In common with other poxviruses, orf virus (ORFV) is believed to induce drastic changes in the host intracellular environment through expression of an arsenal of virulence factors. The ankyrin repeat (ANK) proteins are ... -
Characterising the role of Vascular ENaC for Blood Pressure Regulation
Hypertension is characterised by extracellular fluid volume expansion and increased vascular tone. The epithelial sodium channel (ENaC) in the kidney has a central role in maintenance of extracellular fluid volume. In the ... -
Effect of Prolactin on Voluntary Running Behaviour and Locomotion
The regulation of energy expenditure is crucial for maintenance of energy balance within individuals across variable environments. Neuroendocrine regulation of energy expenditure employs multiple neural populations across ... -
Impact of Dietary Fatty Acids on Neuronal and Metabolic Health
In the past decades, the worldwide prevalence of obesity has nearly trebled. This trend is mainly caused by the permanent availability of food, the consumption of a Western-style diet, and the sedentary lifestyle of our ... -
The involvement of the multiple drug resistance family in facial eczema resistance
Facial Eczema (FE) is a disease of ruminants that was first reported in New Zealand at the beginning of this century. Today this disease is considered the most important mycotoxin affecting the sheep industry, causing an ... -
Investigating How Mutations in Cytochrome c Affect the Intrinsic Apoptosis Pathway
Cytochrome c is a highly conserved, haem containing protein that usually resides in the mitochondria inter-membrane space. In mitochondria, cytochrome c has a well-known role in the electron transport chain transferring ... -
Ghrelin and peripheral artery disease
Peripheral artery disease (PAD) is the most common cardiovascular disease associated with type 2 diabetes mellitus (T2DM). PAD is characterised by the narrowing or occlusion of systemic arteries impeding blood supply to ... -
The PvdF enzyme of Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic bacterium which requires iron for growth and survival. Under iron limiting conditions, P.aeruginosa secrete iron scavenging compounds called pyoverdines. Pyoverdines consist of a ... -
Understanding antimicrobial and antiseptic resistance relationships in Staphylococcus aureus
Staphylococcus aureus is an opportunistic pathogen that causes skin infections, bacteraemia, and endocarditis in humans. In New Zealand, the common lineage of S. aureus is the ST1 lineage which harbours a fusidic acid ... -
Prehistoric diet and health in the western Pacific Islands
The mode of subsistence of the earliest populations that colonised Remote Oceania, the people associated with the Lapita Cultural Complex, remains a contentious issue and, for many Pacific islands, the extent to which ... -
Developing Plasmodium cynomolgi culture as a model to investigate antimalarial effects on Plasmodium vivax
The ability to culture pathogenic organisms enables researchers to understand the biology of the organism which aids in the development of vaccines and drugs. Hence the establishment of the protocol for the in vitro ... -
Elucidating the effect of prenatal androgen excess on male reproductive function
The in utero nutritional and hormonal environment is critical in shaping the developing male and female reproductive systems. Elevated in utero androgen exposure has been correlated with the manifestation of abnormal ... -
Anti-Cancer Mechanism of Phenyl Selenides in Breast Cancer
Breast cancer can be divided into a number of subtypes based upon receptor expression. Of these triple-negative breast cancer (TNBC) is the most aggressive subtype and is highly challenging to treat, as it has no targeted ... -
Antibacterial properties of lactic acid bacteria for meat bio-preservation
Some lactic acid bacteria (LAB) are capable of growing on stored meat and inhibiting pathogenic and spoilage bacteria of concern to the meat industry using a range of mechanisms including general competition and/or the ... -
Title Characterisation of the amphibian pathogenic fungus Batrachochytrium dendrobatidis supercontig 5
Amphibian species have been experiencing a massive global decline during the past few decades. Chytridiomycosis, caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd), is a cutaneous infectious disease that leads ... -
The Twilight Zone of Nucleotide Homology
Homology search tools are important for inferring homology in the abundance of genomes currently sequenced. These tools utilise sequence similarity in order to assign a score between two sequences from which homology is ...