University of Otago, Christchurch School of Medicine and Health Sciences
Collections in University of Otago, Christchurch School of Medicine and Health Sciences
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Anaesthesia [3]
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Population Health [25]
Recent Deposits
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Clinical guideline use and compliance: examining variation from the clinical pathway
Introduction Clinical guidelines are developed with the aim of optimising patient care and have been shown to improve both clinical outcomes and the care process. ‘Hospital HealthPathways’ are guidelines published for use ... -
Gene Modification of Breast Cancer Cells for Cancer Imaging
Human epidermal growth factor receptor 2 (HER2) is a prominent breast cancer cell surface receptor that is overexpressed in approximately 20-30% of breast cancer tumours. Trastuzumab (Herceptin) is an effective clinical ... -
Peroxiredoxins as biomarkers of oxidative stress in metastatic melanoma cells
Melanoma is one of the most common forms of skin cancer, and is particularly prevalent in New Zealand and Australia. If detected early, surgery may be curative; however, once metastatic there are very few effective treatments ... -
Exploring the information needs of people with mild dementia and their care partner, post-diagnosis at a Memory Clinic.
Background It is essential that information needs are met throughout the dementia continuum to improve the quality of life of both the care partner and person with dementia. A crucial information opportunity is soon after ... -
Staphylococcus aureus survival inside the neutrophil phagosome
Neutrophils are a key component of the innate immune system, functioning to locate, phagocytose and destroy invading pathogens. Engulfed bacteria are internalized into a vacuole called the phagosome, which is subsequently ... -
An integrative literature review of nurse-led interventions for the prevention and management of cardiovascular disease
Background Cardiovascular disease is the leading cause of death and premature mortality and is estimated to cause 40% of all deaths and 33 percent of life years lost between 45 and 64 years of age in New Zealand (New ... -
Transcriptional effects of mood stabiliser drugs in a serotonergic cell line
Sodium valproate (VPA) and lithium are drugs of different chemical classes that are widely prescribed in the treatment of bipolar disorder (BD). Molecular and pharmacological studies have revealed some relevant properties ... -
Bioavailability and biological effects of isothiocyanates from broccoli sprout powder
Broccoli sprout powder (BSP) is a rich source of glucosinolates that can be hydrolysed to isothiocyanates by enzyme myrosinase when the powder comes into contact with water. The major isothiocyanate produced in broccoli ... -
B-Type Natriuretic Peptide and Novel Cardiac Ultrasound in Very Preterm Neonates: Potential Markers for the Detection of Pulmonary Hypertension and for Risk Stratification
Very premature birth causes an interruption of cardiorespiratory development. Successful pulmonary adaptation requires synchronous development of alveoli and pulmonary capillary networks. Very premature birth threatens ... -
Experiences of mentoring in primary health care settings : registerd nurses' and students' perspectives
This research provides an in-depth case study of eight undergraduate nursing students and eight Registered Nurses' experiences of mentoring during clinical placements in general practice. Each student was supported in ... -
Nurses' knowledge and attitudes regarding pain
Background: Nurses have a crucial role in the assessment and management of pain in the care of the postoperative patient. However, international research has shown significant numbers of nurses surveyed had knowledge and ... -
Medication adherence rates and beliefs about medications among New Zealand adults with Inflammatory Bowel Disease
Background Inflammatory Bowel Disease (IBD) refers to Ulcerative colitis (UC) or Crohn’s disease (CD) and is a global problem, affecting over five million people worldwide. Rates of IBD have been reported to be particularly ... -
The caregiver experience of haematopoietic stem cell transplant for haematological malignancy within the provincial New Zealand setting.
Background Haematopoietic stem cell transplant (HSCT) - also known as 'bone marrow transplant' or 'stem cell transplant' - is an intensive treatment which may be used to treat patients with blood cancer such as leukaemia, ... -
Mindfulness, Acceptance, and Meaning in Life for Adults with Advanced Cancer
Introduction When cancer is advanced and life-threatening, it has both physical and psychological effects, and for many people creates existential concerns. Mindfulness as a therapeutic endeavour is widely used in ... -
Suffering, Solidarity and Spirituality: The Lived Experiences of Internally Displaced Women in Northern Nigeria
Since 2009, the Nigerian state, has been under intense attack by an Islamic extremist group popularly known as Boko Haram. As a result of the insurgency, over two million persons have been internally displaced, 53% of whom ... -
Collaboration with and for Rural Māori with Substance use and Related Problems
Collaboration is argued to be a necessary process in the effective treatment of people experiencing substance use and related problems. The process of collaboration is proposed to guide practitioners within services to ... -
Androgens and the Female Brain: The Relationship between Testosterone Levels, Depression, Anxiety, Cognitive Function, and Emotion Processing in Females with Polycystic Ovarian Syndrome
Background: Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder in reproductive-aged females, with the main hormonal abnormality being androgen (testosterone) excess. Although it is well-established ... -
The New Zealand Osteopathic Profession’s Understanding of Continuing Professional Development
Continuing professional development (CPD) is commonly accepted as the process for improving the competency, and enhancing the knowledge, skills and attitudes (KSA’s) of health professionals. Within the last few decades CPD ... -
Finding the Balance: Family inclusive practice in adult community mental health
Despite family involvement and participation being strongly recommended in mental health services policies and guidelines, the evidence suggests that this is not always implemented effectively. It is evident from the ... -
In what way does a history of mental illness affect the response received when service users come into contact with the police service and does the presence of mental illness change the decision making of the police with regard to potential prosecution
BACKGROUND The Ministry of Health reports that on average 150,000 New Zealand people are seen by mental health and addiction services each year. Of this group, a percentage enter mental health services following involvement ...