University of Otago, Christchurch School of Medicine and Health Sciences
Collections in University of Otago, Christchurch School of Medicine and Health Sciences
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Anaesthesia [3]
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Population Health [25]
Recent Deposits
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An exploration of the experiences of registered nurses working in aged residential care facilities regarding interRAI: A qualitative research design
Abstract Title An exploration of the experiences of registered nurses’ working in aged residential care facilities regarding interRAI: A qualitative research design. Aim To assess the experiences of RNs’ working in aged ... -
Characterising the activity of peroxidasin in the extracellular matrix
Peroxidasin is a rising star in the field of redox biology. It is a peculiar heme peroxidase that uniquely contains non-catalytic domains in addition to the peroxidase domain. Peroxidasin catalyses the formation of an ... -
Self-management outcome measures for children with inflammatory bowel disease
Paediatric Inflammatory Bowel Disease (IBD) can significantly affect a child’s physical and psychological well-being, and the incidence is increasing globally. An emerging focus of paediatric IBD care that has the potential ... -
Role of cancer associated adipocytes (CAA) and tumour associated collagen structures (TACS) in breast cancer cell invasion and metastasis
In post-menopausal breast cancer, obesity is related to invasive tumours that are resistant to chemotherapy and have a poor outcome. Recent research has revealed that adipocytes co-cultured with breast cancer cells ... -
The influence of aspects of the biophysical environment on ovarian cancer cell behaviour
It has been increasingly acknowledged that the extracellular physical environment plays a vital role in cancer development and progression. However, the precise mechanisms of how the biophysical extracellular environment ... -
Scoping for RNA biomarkers in colorectal cancer
Colorectal cancer (CRC) is a major health problem worldwide and a significant issue in New Zealand. Treatment for patients with CRC is morbid and costly, involving a combination of surgery, radiotherapy and chemotherapy. ... -
Oxidant generation by Streptococcus pneumoniae associated with neutrophil extracellular traps
Streptococcus pneumoniae are a common human pathogen, and the leading cause of community-acquired pneumonia world-wide. They have been shown to survive neutrophil extracellular traps (NETs), which are chromatin structures ... -
'You can't hate yourself thin' Obesity recovery and self-compassion
Obesity is a major public health concern in the developed, and increasingly in the developing world. One theory aimed at understanding the aetiology of obesity proposes that highly palatable foods may have addictive ... -
Characterising the relationship between Legionella longbeachae and their amoebal hosts: Implications for Legionnaires' disease prevention
In New Zealand, Legionella longbeachae is the leading cause of Legionnaires’ disease, a severe form of pneumonia that often results in hospitalisation and an intensive course of treatment. Every year, during spring and ... -
Clinical guideline use and compliance: examining variation from the clinical pathway
Introduction Clinical guidelines are developed with the aim of optimising patient care and have been shown to improve both clinical outcomes and the care process. ‘Hospital HealthPathways’ are guidelines published for use ... -
Gene Modification of Breast Cancer Cells for Cancer Imaging
Human epidermal growth factor receptor 2 (HER2) is a prominent breast cancer cell surface receptor that is overexpressed in approximately 20-30% of breast cancer tumours. Trastuzumab (Herceptin) is an effective clinical ... -
Mycobacterial resistance to neutrophil oxidants
Neutrophils are one of the first immune cells to respond when lungs are infected with Mycobacterium tuberculosis – the world’s leading infectious killer that results in millions of deaths every year. Normally, neutrophils ... -
Peroxiredoxins as biomarkers of oxidative stress in metastatic melanoma cells
Melanoma is one of the most common forms of skin cancer, and is particularly prevalent in New Zealand and Australia. If detected early, surgery may be curative; however, once metastatic there are very few effective treatments ... -
Exploring the information needs of people with mild dementia and their care partner, post-diagnosis at a Memory Clinic.
Background It is essential that information needs are met throughout the dementia continuum to improve the quality of life of both the care partner and person with dementia. A crucial information opportunity is soon after ... -
Staphylococcus aureus survival inside the neutrophil phagosome
Neutrophils are a key component of the innate immune system, functioning to locate, phagocytose and destroy invading pathogens. Engulfed bacteria are internalized into a vacuole called the phagosome, which is subsequently ... -
An integrative literature review of nurse-led interventions for the prevention and management of cardiovascular disease
Background Cardiovascular disease is the leading cause of death and premature mortality and is estimated to cause 40% of all deaths and 33 percent of life years lost between 45 and 64 years of age in New Zealand (New ... -
Transcriptional effects of mood stabiliser drugs in a serotonergic cell line
Sodium valproate (VPA) and lithium are drugs of different chemical classes that are widely prescribed in the treatment of bipolar disorder (BD). Molecular and pharmacological studies have revealed some relevant properties ... -
Bioavailability and biological effects of isothiocyanates from broccoli sprout powder
Broccoli sprout powder (BSP) is a rich source of glucosinolates that can be hydrolysed to isothiocyanates by enzyme myrosinase when the powder comes into contact with water. The major isothiocyanate produced in broccoli ... -
B-Type Natriuretic Peptide and Novel Cardiac Ultrasound in Very Preterm Neonates: Potential Markers for the Detection of Pulmonary Hypertension and for Risk Stratification
Very premature birth causes an interruption of cardiorespiratory development. Successful pulmonary adaptation requires synchronous development of alveoli and pulmonary capillary networks. Very premature birth threatens ... -
Experiences of mentoring in primary health care settings : registerd nurses' and students' perspectives
This research provides an in-depth case study of eight undergraduate nursing students and eight Registered Nurses' experiences of mentoring during clinical placements in general practice. Each student was supported in ...