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Plasma microRNA biomarkers in rectal cancer patients undergoing neoadjuvant therapy
Colorectal cancer (CRC) is the second most common cause of cancer related death worldwide with an expected 1.8 million new cases this year (1). CRC claims approximately 1200 New Zealand lives per year and rectal cancer ...
Improving the assessment process for patients presenting with acute (non-traumatic) abdominal pain to the general surgery department.
Background Abdominal pain is a very common but also challenging presentation to general surgery. A number of implementations have been introduced to improve the diagnostic process. These include: ED 4-6 hour targets, acute ...
Examining fatigue and performance in critical care clinicians
Background: Fatigue related to sleep deprivation has a degrading effect on human performance. In critical care health settings this represents a potential hazard to the safety of patients. This thesis aimed to identify and ...
High Altitude Medicine: Understanding the Mechanism of Acute Mountain Sickness
The present study was undertaken to determine the integrative physiology behind acute mountain sickness (AMS) susceptibility. We compared the respiratory, cardiovascular, renal and cerebrovascular responses to acute ...
Cold and Crowded - The Early Childhood Education Environments Study
Background
In recent decades New Zealand has seen a growth in the use of childcare as a weekday living environment for children under five years old, with an increasing proportion of children attending, and children ...
'Liking' working with suicidal patients: A mixed methods research investigation of clinicians' positive inclination to patients at risk for suicide and the effect of this on the therapeutic encounter
Background: A strong therapeutic relationship is associated with better outcome in therapy/treatment, including with patients at risk for suicide (PRS). However, to build a strong therapeutic relationship with PRS, clinicians’ ...
Business influences on government decisions affecting public health: a case study from Australia and New Zealand
The aim of this thesis is to enable a better understanding of how business power influences government policy decisions when there is conflict between business and public health objectives. This is to support more effective ...
Role of New Zealand Community Pharmacists in Opioid Substitution Treatment
Introduction: Opioid dependence is a chronic relapsing health condition affecting thousands of New Zealanders. Opioid Substitution Treatment (OST), dispensed regularly by community pharmacists (CPs), is a well-recognised ...
Metaphor in Cognitive Behaviour Therapy
Metaphors are common in psychotherapy. Over the last decade, there has been increasing interest in the use of metaphor in cognitive behaviour therapy (CBT), with attention to client metaphors being asserted as a way of ...
ADSC-EVs and Macrophage Polarization in Fat Grafting for Breast Reconstruction
Breast Cancer is the most commonly diagnosed cancer among women in New Zealand, with an estimated 3000 women diagnosed in New Zealand every year. The most common form of treatment is surgery, and following treatment, the ...