Oral Diagnostic and Surgical Sciences

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Recent Deposits

The differential regulation of Signal Transducer and Activator of Transcription-3 pathway under Endoplasmic Reticulum Stress in Oral Squamous Cell Carcinoma

Yakin, Muhammed Ihsan Jameel (Thesis, Doctor of Clinical Dentistry, 2016)

Background Signal transducer and activator of transcription (STAT)-3 lies at the convergence point of key pathways involved in many malignancies including oral squamous cell carcinoma (OSCC). Endoplasmic reticulum (ER) ...
Lymphangiogenesis in Oral Squamous Cell Carcinoma

Chutipongpisit, Kullasit (Thesis, Doctor of Clinical Dentistry, 2016)

Background: Lymphangiogenesis, the formation of new lymphatic vessels, is an essential process in normal growth and development and wound healing. It is also observed in pathological processes including tissue inflammation ...
Role of interleukin 17 in progression of oral squamous cell carcinoma

Avadhani, Avadhoot (Thesis, Doctor of Philosophy, 2016)

IL17 is a pro-inflammatory cytokine with increased gene expression in some cancers. It has been demonstrated to exhibit both pro- and anti-tumour effects. The pro-tumour effects of IL17 are mediated either by inducing the ...
Oral Candida Carriage and Antifungal Susceptibility in Patients Receiving Antipsychotic Medication

Mohamed Thani, Wan Syasliza (Thesis, Doctor of Clinical Dentistry, 2015)

Objective: The overall objective of this project was to investigate oral Candida carriage and antifungal susceptibility of Candida albicans isolates in patients receiving antipsychotic medications. Specific objectives ...
The accuracy of cone beam computed tomography (CBCT) to determine newly formed bone within grafted maxillary sinus in sheep

Ko, David (Seung Young) (Thesis, Doctor of Clinical Dentistry, 2015)

Grafting of the maxillary sinus floor has become a common surgical intervention to increase bone volume for implant placement (Wallace and Froum, 2003); the procedure can be performed either as an 1-stage procedure with ...
Management of Xerostomia Following Radiotherapy: A clinical trial of a novel emulsion for potential use as a saliva substitute

Apperley, Olivia (Thesis, Doctor of Clinical Dentistry, 2015)

Aim: Researchers have recently developed a novel oily formulation for potential us as a saliva substitute. The aim of this randomised, cross-over study is to compare this new formulation to a currently available saliva ...
Expression of cyclin D1 and its correlation with p27KIP1 in non-neoplastic and non-dysplastic mucosa, oral epithelial dysplasia and oral squamous cell carcinoma

Guan, Guangzhao (Thesis, Doctor of Clinical Dentistry, 2014)

Background Oral and pharyngeal cancer accounts for one-sixth of the total cancers worldwide. An estimated 263,900 new cases and 128,000 deaths from oral cavity cancer (including lip cancer) occurred in 2008 worldwide. ...
Expression of FoxP3, IL17, IL33, and IL35 in Oral Lichen Planus

Javvadi, Lakshmi Ramya (Thesis, Doctor of Clinical Dentistry, 2014)

Introduction Oral lichen planus (OLP) is a complex immunological disorder of oral mucosa, mediated in part by the release of cytokines by activated T-cells. Of late, two closely related T-helper (Th) cell subsets; regulatory ...
Living with dry mouth – Sjögren’s patients’ perspectives

Ngo, Di Ying Joanna (Thesis, Doctor of Clinical Dentistry, 2014)

Aim The aim of this qualitative study was to provide clinicians with insight into how dry mouth can impact on the daily lives of Sjögren’s Syndrome (SS) patients. SS is an autoimmune exocrinopathy characterised by lymphocytic ...
Does Submersion in a Seawater Environment Affect the Retrieval of Useful DNA from Teeth?

Drake, Sarah Michelle (Thesis, Doctor of Clinical Dentistry, 2014)

Definitive post-mortem identification of human remains currently involves identification by visual means, fingerprinting, dental identification or DNA analysis. It is generally agreed that teeth provide the most protected ...
Angiogenic Factors in Oral Cancer

Allsobrook, Olive Florence Louise (Thesis, Doctor of Clinical Dentistry, 2014)

Angiogenesis is a key factor in normal development and in the development and progression of most malignancies, including oral cancer. It is also an integral component of some inflammatory hyperplastic lesions including ...
The development of special needs dentistry service in Malaysia - a situational analysis (based on New Zealand experience)

Hamzah, Siti Zaleha (Thesis, Doctor of Clinical Dentistry, 2010)

Aim: The aim of this project is to understand the expectations of the Malaysian population for future development of Special Needs Dentistry (SND) service in Malaysia. Along with the current recognition of the specialty ...
Oral Squamous Cell Carcinoma: Comparing the occurrence of this disease in New Zealand and the Fiji Islands (2000-2010)

Gavidi, Ratu Osea (Thesis, Doctor of Clinical Dentistry, 2013)

Introduction: Oral and oropharyngeal cancer is the sixth most common cancer in the world. The most common type of cancer occurring in the oral and oropharyngeal area is oral squamous cell carcinoma (OSCC). For the purposes ...
Immune Responses in Primary Oral Squamous Cell Carcinoma and Lymph Node Metastasis

Mohd Hussaini, Haizal (Thesis, Doctor of Philosophy, 2013)

Background: Oral squamous cell carcinoma (OSCC) develops in an immune cell-rich environment, where inflammatory cells in the tumour microenvironment establish an anti-tumour response by secreting pro-inflammatory cytokines. ...
An Evidence Based and Historical Review of War Surgery of the Face and Jaws

Tong, Darryl Chan (Thesis, Doctor of Philosophy, 2013)

War surgery of the face and jaws is a fascinating and complex area of surgery and medicine with a relatively short history of formal development as a specialty despite surgical procedures being performed on this area of ...
Aetiology of denture sore mouth : yeasts and oral hygiene.

Burton, John FitzGerald (Thesis, Master of Dental Surgery, 1971)

PREFACE Denture sore mouth is a localised inflammation of the oral mucosa seen quite commonly in patients wearing full or partial maxillary dentures. Trauma and infection with yeast-like organisms are thought to be ...
Endoplasmic Reticulum Stress and Russell Bodies: Study of the Relationship Using a Periodontal Inflammation Model

Seo, Benedict Lloyd (Thesis, Doctor of Clinical Dentistry, 2011)

The endoplasmic reticulum (ER) is an organelle of great importance. It represents the intracellular site for protein synthesis, folding, and post-translational modification. Intricately related processes that oversee the ...
The thickness of parietal bones in a New Zealand sample of cadaveric skulls in relation to calvarial bone graft, 2007-2011

Choi, Han Joon (Thesis, Master of Dental Surgery, 2011)

Objectives: (1) To evaluate the average thickness of the parietal bones in a New Zealand European sample of cadaveric skulls; (2) to construct a thickness map of the parietal bone; and (3) to identify the ideal site(s) for ...
Patterns and trends in facial fractures in New Zealand

Adsett, Luke (Thesis, Doctor of Clinical Dentistry, 2011)

Intro: Fracture of the human facial skeleton is a common injury that places serious burden on society. Severe morbidity, mortality, facial disfigurement, loss of function and financial cost are all associated with facial ...
Oral health of older people admitted to hospital for assessment

Ling, Guo Yean (Thesis, Doctor of Clinical Dentistry, 2011)

Introduction and objectives: New Zealand’s population of older people is increasing, and a corresponding dental transition is occurring, whereby older people are retaining their natural teeth for longer than before. New ...