Oral Diagnostic and Surgical Sciences
Recent Deposits
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Expression of the lysyl oxidase family in odontogenic lesions
Background: The lysyl oxidase family of enzymes consists of five members, namely lysyl oxidase (LOX) and lysyl oxidase-like (LOXL) 1-4. They are secreted enzymes whose function is to stabilise the extracellular matrix via ... -
Lymph nodes as a pre-metastatic niche for oral squamous cell carcinoma
Background Pre-metastatic niche (PMN) is a new concept in the process of metastasis defined as tumour microenvironment at the future metastatic site which is established by the tumour as a preparation before the arrival ... -
Awareness of pre-radiation dental assessment of head and neck cancer patients among dentists in Malaysia and New Zealand
Aims: The aim of this study was to investigate the approaches taken for dental assessment of patients with head and neck cancer (HNCa) by hospital dentists in New Zealand and Malaysia, in order to assist with the development ... -
Third molar surgery outcomes: a comparison between intravenous sedation and general anaesthesia
Objective. To compare intravenous (IV) sedation and general anaesthesia (GA) for third molar surgery in terms of patient anxiety, satisfaction, choice and, oral-health-related quality-of-life (OHRQoL). Study Design. A ... -
Clinicians' Perspectives on Special Care Dentistry in New Zealand
Introduction: Special Care Dentistry in New Zealand is relatively underdeveloped. With its workforce persistently scarce, its training and career pathways remain unclear. Little is understood about the specialty’s role ... -
Lymphangiogenesis in metastatic lymph nodes of oral squamous cell carcinoma
Background: Regional lymph node metastasis is a crucial negative prognostic factor in oral squamous cell carcinoma (OSCC) which significantly reduces survival rates in patients affected. Whilst angiogenic and lymphangiogenic ... -
The differential regulation of Signal Transducer and Activator of Transcription-3 pathway under Endoplasmic Reticulum Stress in Oral Squamous Cell Carcinoma
Background Signal transducer and activator of transcription (STAT)-3 lies at the convergence point of key pathways involved in many malignancies including oral squamous cell carcinoma (OSCC). Endoplasmic reticulum (ER) ... -
Lymphangiogenesis in Oral Squamous Cell Carcinoma
Background: Lymphangiogenesis, the formation of new lymphatic vessels, is an essential process in normal growth and development and wound healing. It is also observed in pathological processes including tissue inflammation ... -
Role of interleukin 17 in progression of oral squamous cell carcinoma
IL17 is a pro-inflammatory cytokine with increased gene expression in some cancers. It has been demonstrated to exhibit both pro- and anti-tumour effects. The pro-tumour effects of IL17 are mediated either by inducing the ... -
Oral Candida Carriage and Antifungal Susceptibility in Patients Receiving Antipsychotic Medication
Objective: The overall objective of this project was to investigate oral Candida carriage and antifungal susceptibility of Candida albicans isolates in patients receiving antipsychotic medications. Specific objectives ... -
The accuracy of cone beam computed tomography (CBCT) to determine newly formed bone within grafted maxillary sinus in sheep
Grafting of the maxillary sinus floor has become a common surgical intervention to increase bone volume for implant placement (Wallace and Froum, 2003); the procedure can be performed either as an 1-stage procedure with ... -
Management of Xerostomia Following Radiotherapy: A clinical trial of a novel emulsion for potential use as a saliva substitute
Aim: Researchers have recently developed a novel oily formulation for potential us as a saliva substitute. The aim of this randomised, cross-over study is to compare this new formulation to a currently available saliva ... -
Expression of cyclin D1 and its correlation with p27KIP1 in non-neoplastic and non-dysplastic mucosa, oral epithelial dysplasia and oral squamous cell carcinoma
Background Oral and pharyngeal cancer accounts for one-sixth of the total cancers worldwide. An estimated 263,900 new cases and 128,000 deaths from oral cavity cancer (including lip cancer) occurred in 2008 worldwide. ... -
Expression of FoxP3, IL17, IL33, and IL35 in Oral Lichen Planus
Introduction Oral lichen planus (OLP) is a complex immunological disorder of oral mucosa, mediated in part by the release of cytokines by activated T-cells. Of late, two closely related T-helper (Th) cell subsets; regulatory ... -
Living with dry mouth – Sjögren’s patients’ perspectives
Aim The aim of this qualitative study was to provide clinicians with insight into how dry mouth can impact on the daily lives of Sjögren’s Syndrome (SS) patients. SS is an autoimmune exocrinopathy characterised by lymphocytic ... -
Does Submersion in a Seawater Environment Affect the Retrieval of Useful DNA from Teeth?
Definitive post-mortem identification of human remains currently involves identification by visual means, fingerprinting, dental identification or DNA analysis. It is generally agreed that teeth provide the most protected ... -
Angiogenic Factors in Oral Cancer
Angiogenesis is a key factor in normal development and in the development and progression of most malignancies, including oral cancer. It is also an integral component of some inflammatory hyperplastic lesions including ... -
The development of special needs dentistry service in Malaysia - a situational analysis (based on New Zealand experience)
Aim: The aim of this project is to understand the expectations of the Malaysian population for future development of Special Needs Dentistry (SND) service in Malaysia. Along with the current recognition of the specialty ... -
Oral Squamous Cell Carcinoma: Comparing the occurrence of this disease in New Zealand and the Fiji Islands (2000-2010)
Introduction: Oral and oropharyngeal cancer is the sixth most common cancer in the world. The most common type of cancer occurring in the oral and oropharyngeal area is oral squamous cell carcinoma (OSCC). For the purposes ... -
Immune Responses in Primary Oral Squamous Cell Carcinoma and Lymph Node Metastasis
Background: Oral squamous cell carcinoma (OSCC) develops in an immune cell-rich environment, where inflammatory cells in the tumour microenvironment establish an anti-tumour response by secreting pro-inflammatory cytokines. ...