Anatomy
Recent Deposits
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The Role of Lhx9 in the Male Reproductive System
Leydig cells (LCs) are found within the interstitium of the testes. LCs are crucial to male reproductive function due to their role in testosterone synthesis, a process vital for both organogenesis and secondary sex ... -
The role of gene duplication and neofunctionalization in the sexual plasticity of teleost fish
Sex determination and differentiation varies widely across vertebrates. In teleost fish these processes are remarkably plastic. In contrast to a gonochoristic system where the sexes are separate, fish that begin life as ... -
A novel leptin receptor mutation causes delayed puberty onset in mice
Reproductive function is tightly controlled by nutritional state due to its high energetic demands. Regulation of fertility according to available energy stores is attained through the integration of metabolic status signals ... -
Kinetics of Passive Demethylation
DNA methylation is an epigenetic modification established during cellular differentiation, and when removed by either active or passive means, can substantially improve the efficiency by which induced pluripotent stem cells ... -
Characterisation of developmental cues in early postnatal AgRP neurons
Body weight regulation and the control of food intake are topics that continue to receive much attention as countries around the world grapple with alarming rates of obesity and the associated poorer health outcomes. Central ... -
The role of calcium-permeable AMPA receptors and arc in secreted amyloid precursor protein alpha-mediated plasticity
The orchestrated regulation of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-subtype of glutamate receptors by neuronal activity and neuromodulators is critical to the expression of both long-term ... -
Implications of human interaction for health of past populations in Asia
Drivers of human mobility such as migration, trade and conflict is today recognised to considerably influence the spread and prevalence of infectious diseases globally. Additionally, these factors are known to impact ... -
Modulation of interhemispheric inhibition and its effect on stroke recovery in the rat
Rationale: Residual disability following stroke is a significant challenge for patients and the healthcare system, both in New Zealand and worldwide. Poor recovery from motor cortex (M1) stroke has been associated with an ... -
Assessment of the impacts of anthropogenic hybridisation in a threatened non-model bird species through the development of genomic resources with implications for conservation
Interspecific hybridisation—the breeding between distinct species—can contribute to species extinction due to wasted reproductive potential, outbreeding depression, and introgression of genetic material mediated by ... -
The prehistoric people from Sigatoka : an analysis of skeletal and dental traits as evidence of adaptation
The biological relationships of Pacific people has long been the subject of conjecture and research. Yet very few skeletons older than 1000 years have been recovered and studied. The excavation of 63 skeletons from the ... -
Stress and sex change in New Zealand spotty wrasse (Notolabrus celidotus)
Sex is fixed from birth in most organisms, where individuals develop as either female or male and retain their sex through life. Traditionally, sex has been considered to be determined by genetic elements or by environmental ... -
Microbial bioerosion: testing a new technique to differentiate stillborn, perinatal, and neonatal infants in archaeological samples.
First reported by Carl Wedl in 1864, microbial bioerosion is one of the most common and destructive taphonomic processes to act on skeletal material within the archaeological record. It refers to when microbes such as ... -
DNA methylation memory: Understanding epigenetic reprogramming in vertebrates
DNA methylation is an epigenetic mark critical for vertebrate development and is associated with numerous cellular and organismal processes including X-chromosome inactivation, genomic imprinting, and regulation of gene ... -
The mortuary practices of three prehistoric sites in northeast Thailand : an interpretation from the perspective of field anthropology
Burials from archaeological sites contain important information and differences between them suggest that the members of a community interred their dead in a specific and intentional manner. To form a comprehensive ... -
A Novel Oocyte Cryopreservation Method using High Pressure Freezing
Oocyte cryopreservation (egg freezing) involves freezing a female’s oocytes in order to preserve her fertility. These oocytes can later be thawed and fertilised in vitro when she is ready to begin fertility treatment. Women ... -
Validation and Characterisation of Novel miRNAs Identified in the E15.5 Mouse Brain
MicroRNAs (miRNAs) are small noncoding elements that downregulate gene expression and play an important role in maintaining robust neurodevelopment. Since abnormal expression of miRNAs has been associated with disorders ... -
Validation and Characterisation of Novel miRNAs Identified in the E15.5 Mouse Brain
MicroRNAs (miRNAs) are small noncoding elements that downregulate gene expression and play an important role in maintaining robust neurodevelopment. Since abnormal expression of miRNAs has been associated with disorders ... -
Assessing the efficacy of a fluorescent model of the ovarian reserve in mice
In mammalian females, germ cells proliferate exclusively in development resulting in a finite number of oocytes at birth which are kept in a dormant state within primordial follicles. The ovarian reserve (OR) is the ... -
Prolactin Receptor Expression In The Mouse Brain
We used a novel knock‐in mouse strain in which Cre recombinase is expressed together with the long isoform of the Prlr using an internal ribosome entry site (IRES). By crossing this Prlr‐IRES‐Cre mouse with a tau green ... -
Characterisation of hypothalamic leptin resistance during pregnancy in the rat
Leptin is primarily an adipose-derived hormone that acts in the hypothalamus to regulate body fat levels by suppressing appetite and increasing metabolic rate. Pregnancy is characterised by increased food intake and fat ...