Anatomy
Recent Deposits
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DNA methylation memory: Understanding epigenetic reprogramming in vertebrates
DNA methylation is an epigenetic mark critical for vertebrate development and is associated with numerous cellular and organismal processes including X-chromosome inactivation, genomic imprinting, and regulation of gene ... -
The mortuary practices of three prehistoric sites in northeast Thailand : an interpretation from the perspective of field anthropology
Burials from archaeological sites contain important information and differences between them suggest that the members of a community interred their dead in a specific and intentional manner. To form a comprehensive ... -
A Novel Oocyte Cryopreservation Method using High Pressure Freezing
Oocyte cryopreservation (egg freezing) involves freezing a female’s oocytes in order to preserve her fertility. These oocytes can later be thawed and fertilised in vitro when she is ready to begin fertility treatment. Women ... -
Validation and Characterisation of Novel miRNAs Identified in the E15.5 Mouse Brain
MicroRNAs (miRNAs) are small noncoding elements that downregulate gene expression and play an important role in maintaining robust neurodevelopment. Since abnormal expression of miRNAs has been associated with disorders ... -
Validation and Characterisation of Novel miRNAs Identified in the E15.5 Mouse Brain
MicroRNAs (miRNAs) are small noncoding elements that downregulate gene expression and play an important role in maintaining robust neurodevelopment. Since abnormal expression of miRNAs has been associated with disorders ... -
Assessing the efficacy of a fluorescent model of the ovarian reserve in mice
In mammalian females, germ cells proliferate exclusively in development resulting in a finite number of oocytes at birth which are kept in a dormant state within primordial follicles. The ovarian reserve (OR) is the ... -
Prolactin Receptor Expression In The Mouse Brain
We used a novel knock‐in mouse strain in which Cre recombinase is expressed together with the long isoform of the Prlr using an internal ribosome entry site (IRES). By crossing this Prlr‐IRES‐Cre mouse with a tau green ... -
Characterisation of hypothalamic leptin resistance during pregnancy in the rat
Leptin is primarily an adipose-derived hormone that acts in the hypothalamus to regulate body fat levels by suppressing appetite and increasing metabolic rate. Pregnancy is characterised by increased food intake and fat ... -
The role of Lbx1 expression in a mouse model of Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis is a disease of the spine, affecting between 1-3% of the population. This disease manifests as a lateral curvature of the spine that can lead to a range of symptoms such as back pain and ... -
Arginine metabolism and tauopathies
Tauopathies refers to a group of neurodegenerative diseases characterized by the intracellular accumulation of hyperphosphorylated tau protein. Whereas Alzheimer’s disease (AD) is an example of secondary tauopathy, ... -
The cellular and molecular mechanisms underpinning childhood absence epilepsy: An investigation of dysfunctional inhibitory microcircuits and the role of SOM+ inhibitory interneurons
Childhood absence epilepsy (CAE) is a generalised, non-convulsive subtype of epilepsy, accounting for 10-17% of all childhood epilepsies. Absence seizures are characterised by a brief loss of consciousness accompanied by ... -
The relationship between the long posterior sacroiliac ligament and the posterior sacrococcygeal plexus
The burden of non-specific low back pain in the population is substantial. Putative sacroiliac joint pain or 'sacroiliac syndrome' is a significant subset of this condition. Localisable pain over the long posterior sacroiliac ... -
Temporomandibular joint pathological changes in the prehistoric New Zealand Maori and Moriori
Diseases and disorders of the temporomandibular joint are commonly encountered clinically. This has lead to most temporomandibular research focusing upon the pathologies that affect the joint and their proposed aetiologies. ... -
The Role of Kisspeptin Neurons in Mediating Prolactin-Induced Suppression of LH Secretion
Hyperprolactinaemia is one of the major causes for infertility. It is well-established that elevated prolactin levels suppress the pulsatile release of gonadotropin-releasing hormone (GnRH) from the hypothalamus, and ... -
Endothelial nitric oxide synthase deficiency – implications for Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and neuropathological hallmarks of amyloid-β (Aβ ) plaques and neurofibrillary tangles, with aging as a major risk factor. ... -
The Health Impacts of Increasing Social Inequality in Late Prehistoric Northeast Thailand
Evidence for increasing social inequality and a concurrent health deterioration has been observed in Iron Age (420BCE-500CE) northeast Thailand. Inequality is commonly considered to be represented by variations in quantities ... -
Clinical and Surgical Anatomy of the Ligament of the Head of Femur
The ligament of the head of femur (LHF), or ligamentum teres, is an intra-articular ligament of the hip joint, running between the transverse acetabular ligament (TAL) of the hip and the fovea capitis femoris (FCF) on the ... -
Maternal obesity affects neurogenesis in the lateral hypothalamic area
Many human epidemiological studies have reported maternal obesity confers an increased risk for obesity and metabolic disorders within the offspring. Additionally this effect has been observed in numerous animal models of ... -
Effect of Prolactin on Voluntary Running Behaviour and Locomotion
The regulation of energy expenditure is crucial for maintenance of energy balance within individuals across variable environments. Neuroendocrine regulation of energy expenditure employs multiple neural populations across ... -
Prehistoric diet and health in the western Pacific Islands
The mode of subsistence of the earliest populations that colonised Remote Oceania, the people associated with the Lapita Cultural Complex, remains a contentious issue and, for many Pacific islands, the extent to which ...