Anatomy
Recent Deposits
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Anatomy of microvenous valves of normal and venous ulcerated lower limbs
Venous disease is a very common disease that affects millions of people worldwide. While some of the factors that cause the development of varicose veins are well understood, the aetiology of venous ulceration is poorly ... -
Agriculture in Northern Chile’s Atacama Desert: Implications for Human Skeletal and Dental Growth of Early Pre-Hispanic Populations
This project tests the theoretical model predicting human health deterioration with the development and intensification of agriculture in northern Chile (Cohen and Armelagos 1984). Research from North America and Europe ... -
Changes in AMPA Receptor Subunit Expression in the Somatosensory Cortex of the Stargazer Mouse Model of Absence Epilepsy
Childhood absence epilepsy (CAE) is the most common early-onset epilepsy accounting for about 10-17% of all paediatric epilepsies. It is a genetic generalized, non-convulsive form of epilepsy characterized by a sudden and ... -
The regulation and function of the transcription factor Lhx9 during mouse limb and urogenital development.
Developmentally important genes often have pleiotropic effects, being involved in and necessary for multiple developmental processes. An example of this is the LIM- homeobox gene, Lhx9, a transcription factor required for ... -
The impact of high and low-intensity transcranial magnetic stimulation on measures of cortical excitability
In recent decades, transcranial magnetic stimulation (TMS) has emerged as one of the most promising techniques for clinical therapies. It has been proposed for use in a wide number of neurophysiological disorders including ... -
Stereological analysis of the normal red nucleus, and the effect of delayed treatment with adult-sourced adipose-derived mesenchymal stem cells on neonatal hypoxic-ischemic brain injury and motor skills, in the rat
The red nucleus (RN) was investigated first to provide important data for the transfer of information through the RN and to learn key stereological methods that were then applied to the stem cell study. Six male rats, and ... -
Lhx9 is required for urogenital ridge development and ovarian function
While there has been extensive research into the differentiation of sexually dimorphic gonads, there is much to learn about the bi-potential structure they arise from, the urogenital ridge (UGR). This gap in knowledge is ... -
Interleukin-6 Signalling in the Murine Adrenal Gland
The adrenal gland is instrumental in the maintenance and restoration of homeostasis. This is mediated in part by catecholamine and glucocorticoid secretion from the adrenal medulla and cortex respectively. The catecholamine ... -
Secreted amyloid precursor protein alpha regulates AMPA receptor synthesis and expression
Amyloid precursor protein, the parent molecule of the neurotoxic amyloid beta protein associated with Alzheimer’s disease, can also liberate the secreted amyloid precursor protein alpha (sAPPα). This molecule facilitates ... -
The role of anti-Müllerian hormone in the brain’s response to steroid hormones
Many sexual dimorphisms that exist in the brain develop in the postnatal period. For males, this is when testosterone levels are minimal and anti-Müllerian hormone (AMH) is elevated. Testosterone requires the enzyme aromatase ... -
To the Caribbean and Beyond: Complete Mitogenomes of Ancient Guinea Pigs (Cavia porcellus) as a proxy for Interaction in the Late Ceramic Age.
The late ceramic age in the Caribbean occurred from AD500 and was associated with increased interaction between the islands and mainland South America. The domestic guinea pig (Cavia porcellus) was introduced to the Caribbean ... -
Effects of Gestational Nutrition on Post-Natal Fertility in Sheep
Changes to feed availability resulting from global climate change have the potential to exacerbate fertility issues already facing the NZ livestock industry. Appropriate feeding levels during gestation is gaining more ... -
Infant and childhood growth and developmental stress during the intensification of agriculture at Ban Non Wat, Thailand.
The adoption and intensification of agriculture resulted in several alterations within the physical and socio-cultural environment that had long-term consequences on human health in many parts of the world. This thesis ... -
The Cellular Effects of Transcranial Magnetic Stimulation in vivo in the rat
Transcranial magnetic stimulation (TMS) is a form of non-invasive brain stimulation. A magnetic field is pulsed through the skull and into the brain where it induces electrical currents in underlying tissue and activates ... -
Memory HQ: the possible central role of the epigenome in maintaining LTP.
Plasticity mechanisms such as long-term potentiation (LTP) are believed to underlie the formation and maintenance of memories. LTP induction stimulates downstream signalling pathways that lead to changes in gene expression ... -
The reticular thalamic nucleus: revealing a novel phenotype of neurons and describing changes in a rat model of Parkinson’s disease.
The reticular thalamic nucleus (RTN) is a thin band of neurons that lies between the cortex and the rest of the thalamus. Most of the inputs to the nucleus are from collateral axons of thalamocortical and corticothalamic ... -
Excitatory ionotropic glutamate receptor expression in the reticular thalamic nucleus in a mouse model of absence epilepsy
Absence epilepsy refers to a group of genetic, generalized epilepsy syndromes associated with absence seizures, which are especially common in children and juveniles. Childhood absence epilepsy (CAE) is the most prevalent ... -
Does prolactin act directly on AgRP neurons in the arcuate nucleus?
The development of a positive energy balance occurs during pregnancy to support the growth of fetal and maternal tissues, and to increase energy stores in preparation for the metabolic demands of lactation. Leptin levels ... -
Effects of maternal immune activation on brain arginine metabolism and microglia during neonatal neurodevelopment
Schizophrenia is a debilitating chronic mental disorder with prominent frontal and hippocampal dysfunction. While the exact cause of schizophrenia is poorly understood, a number of factors, including neurodevelopmental ... -
Anatomical Characterisation of Prolactin Receptor Expression in the Developing Mouse Brain
Prolactin signalling through the prolactin receptor plays a significant role in many physiological processes. The diverse biological functions attributed to prolactin are largely dependent on the distribution of its receptor. ...