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Does prolactin act directly on AgRP neurons in the arcuate nucleus?
The development of a positive energy balance occurs during pregnancy to support the growth of fetal and maternal tissues, and to increase energy stores in preparation for the metabolic demands of lactation. Leptin levels ...
Functional Analyses of the Neuropeptide FF Receptor System Using GJ14, a Potent and Selective Antagonist
The G-protein coupled neuropeptide FF receptors (NPFFR1 and NPFFR2) belong to the RFamide receptor subfamily. Of these, NPFFR1 is the most widespread and highly expressed receptor in the brain. The endogenous agonist ...
Lapita Plants, People and Pigs
The Lapita cultural complex is associated with the Austronesian expansion out of Island Southeast Asia beginning approximately 3,500 BP. Sites associated with this archaeological culture have been found from the coast of ...
Characterisation of hypothalamic leptin resistance during pregnancy in the rat
Leptin is primarily an adipose-derived hormone that acts in the hypothalamus to regulate body fat levels by suppressing appetite and increasing metabolic rate. Pregnancy is characterised by increased food intake and fat ...
Anatomical and functional characterization of hypothalamic insulin signaling in the metabolic control of reproductive function in mice
Central insulin signaling plays a key role in regulating the neuroendocrine reproductive axis. Mice exhibiting brain-specific insulin receptor gene (Insr) deletion (NIRKO mice) or diabetic insulin insufficiency display ...
Quantitative ultrastructural differences in the cytoplasm of prepubertal lamb and adult ewe oocytes
The ability to breed from juvenile sheep and cattle can increase their lifetime productivity and the rate of genetic gain, and thus increase the profitability of the agricultural industry. Unfortunately, oocytes from ...
Feasibility Studies for Determining Bacterial DNA Profiles from Dental Calculus for Future Applications in Ancient DNA Analysis
The study of ancient DNA is a relatively new field and the methods and standards involved are evolving. DNA isolated from ancient specimens is defined as aDNA. As a DNA source, teeth are the hardest structures of the body ...
The effect of maternal obesity on neural stem cell proliferation in pre natal mice
Autism Spectrum Disorder (ASD) is a complex neurological condition. It affects approximately 1 in 110 people world wide, with a 4:1 ratio of males to females affected. ASD presents with a wide range of psychological symptoms ...
The Anatomy of the Oblique Popliteal Ligament
Purpose: A major structure on the posterior aspect of the knee is the oblique popliteal ligament (OPL). Current literature on the morphology of the ligament is inconsistent and provides minimal quantitative data. The aim ...
Cellular Mechanisms of Prolactin Regulation of Oxytocin Neurons in Reproduction
The hormone oxytocin is secreted from nerve terminals of oxytocin magnocellular cells (MNCs) in the posterior pituitary gland and is important in the timing of birth and is essential for milk secretion. Another reproductive ...