Anatomy: Recently added
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The role of Lbx1 expression in a mouse model of Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis is a disease of the spine, affecting between 1-3% of the population. This disease manifests as a lateral curvature of the spine that can lead to a range of symptoms such as back pain and ... -
Arginine metabolism and tauopathies
Tauopathies refers to a group of neurodegenerative diseases characterized by the intracellular accumulation of hyperphosphorylated tau protein. Whereas Alzheimer’s disease (AD) is an example of secondary tauopathy, ... -
The cellular and molecular mechanisms underpinning childhood absence epilepsy: An investigation of dysfunctional inhibitory microcircuits and the role of SOM+ inhibitory interneurons
Childhood absence epilepsy (CAE) is a generalised, non-convulsive subtype of epilepsy, accounting for 10-17% of all childhood epilepsies. Absence seizures are characterised by a brief loss of consciousness accompanied by ... -
The relationship between the long posterior sacroiliac ligament and the posterior sacrococcygeal plexus
The burden of non-specific low back pain in the population is substantial. Putative sacroiliac joint pain or 'sacroiliac syndrome' is a significant subset of this condition. Localisable pain over the long posterior sacroiliac ... -
Temporomandibular joint pathological changes in the prehistoric New Zealand Maori and Moriori
Diseases and disorders of the temporomandibular joint are commonly encountered clinically. This has lead to most temporomandibular research focusing upon the pathologies that affect the joint and their proposed aetiologies. ... -
The Role of Kisspeptin Neurons in Mediating Prolactin-Induced Suppression of LH Secretion
Hyperprolactinaemia is one of the major causes for infertility. It is well-established that elevated prolactin levels suppress the pulsatile release of gonadotropin-releasing hormone (GnRH) from the hypothalamus, and ... -
Endothelial nitric oxide synthase deficiency – implications for Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and neuropathological hallmarks of amyloid-β (Aβ ) plaques and neurofibrillary tangles, with aging as a major risk factor. ... -
The Health Impacts of Increasing Social Inequality in Late Prehistoric Northeast Thailand
Evidence for increasing social inequality and a concurrent health deterioration has been observed in Iron Age (420BCE-500CE) northeast Thailand. Inequality is commonly considered to be represented by variations in quantities ... -
Clinical and Surgical Anatomy of the Ligament of the Head of Femur
The ligament of the head of femur (LHF), or ligamentum teres, is an intra-articular ligament of the hip joint, running between the transverse acetabular ligament (TAL) of the hip and the fovea capitis femoris (FCF) on the ... -
Maternal obesity affects neurogenesis in the lateral hypothalamic area
Many human epidemiological studies have reported maternal obesity confers an increased risk for obesity and metabolic disorders within the offspring. Additionally this effect has been observed in numerous animal models of ... -
Effect of Prolactin on Voluntary Running Behaviour and Locomotion
The regulation of energy expenditure is crucial for maintenance of energy balance within individuals across variable environments. Neuroendocrine regulation of energy expenditure employs multiple neural populations across ... -
Prehistoric diet and health in the western Pacific Islands
The mode of subsistence of the earliest populations that colonised Remote Oceania, the people associated with the Lapita Cultural Complex, remains a contentious issue and, for many Pacific islands, the extent to which ... -
The morphology of the lumbar paraspinal, gluteal and piriformis muscles in chronic sacroiliac joint pain
The sacroiliac joint (SIJ) can be identified as the source of pain in approximately 10-45% of patients suffering from chronic low back pain. It is hypothesised that SIJ pain may be associated with an imbalance of force ... -
The pathophysiology of the cerebello-thalamic pathway in Parkinson's disease.
Parkinson’s disease (PD) presents with characteristic movement deficits that are thought to evolve as a consequence of degeneration of dopamine neurons in the brain. The degree of PD motor symptoms strongly correlates to ... -
Cognitive Impairment in a Prefrontal Cortex Model of Ischaemia
Every year, millions of people worldwide will have a stroke. For those that survive, many will live with long lasting disabilities, including cognitive impairment. Unfortunately, there are a limited number of preclinical ... -
Balancing Safety and Developmental Potency: Assessing the Effect of Antioxidants and TET on Genomic Imprinting Stability.
Developmental potency represents the ability of undifferentiated cells to undergo transformation into differentiated cells, with specialised functions. The inner cell mass (ICM) of a blastocyst represents the most ... -
Mapping post-stroke brain activation patterns: How do they change over time?
Stroke is a leading cause of death and long-term disability worldwide. Despite decades of research on neuroprotection, only few therapies are currently available to minimise the extent of infarction. As a result, researchers ... -
Investigating the Mechanisms of Prolactin's Role in Maternal Behaviour
Prolactin activity in the medial preoptic area (MPOA) of the hypothalamus has been shown to be essential for the display of maternal behaviours in postpartum female mice. Neuronal outputs from the MPOA that express the ... -
The role of the anterior and ventromedial hypothalamic regions in mediating leptin's effect on fertility
Reproductive function is an energetically demanding process and is therefore tightly regulated by peripheral energy status. This is illustrated by delayed puberty onset and impaired adult reproductive function in individuals ... -
Prolactin receptor expression in the mouse brain
We used a novel knock‐in mouse strain in which Cre recombinase is expressed together with the long isoform of the Prlr using an internal ribosome entry site (IRES). By crossing this Prlr‐IRES‐Cre mouse with a tau green ...