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Interindividual relationships between baroreflex sensitivity and cerebral autoregulation in healthy humans
Maintenance of adequate cerebral perfusion during normal physiological challenges requires integration between cerebral blood flow (CBF) and systemic blood pressure (BP) control mechanisms. Previous studies have shown that ...
Ventricular Fibrillation waveform characteristics
This thesis has explored the information content of the ventricular fibrillation (VF) waveforms recorded as either a surface electrocardiogram (ECG) or an intracardiac electrogram (EGM).
Ventricular fibrillation is lethal ...
Effect of Toll-like Receptor agonists on platelet activation in Acute Coronary Syndromes
Introduction: Platelets express functional Toll-like receptors (TLRs), and numerous studies have found that certain TLR agonists and bacteria are capable of inducing thrombotic and inflammatory responses from isolated ...
Plasma microRNA biomarkers in rectal cancer patients undergoing neoadjuvant therapy
Colorectal cancer (CRC) is the second most common cause of cancer related death worldwide with an expected 1.8 million new cases this year (1). CRC claims approximately 1200 New Zealand lives per year and rectal cancer ...
Improving the assessment process for patients presenting with acute (non-traumatic) abdominal pain to the general surgery department.
Background Abdominal pain is a very common but also challenging presentation to general surgery. A number of implementations have been introduced to improve the diagnostic process. These include: ED 4-6 hour targets, acute ...
ADSC-EVs and Macrophage Polarization in Fat Grafting for Breast Reconstruction
Breast Cancer is the most commonly diagnosed cancer among women in New Zealand, with an estimated 3000 women diagnosed in New Zealand every year. The most common form of treatment is surgery, and following treatment, the ...
The Application of Spectral Analysis of the Surface Electrocardiography Prior to Direct Current Cardioversion in Patients with Persistent Atrial Fibrillation
Aims: The decision of treatment strategy made for atrial fibrillation (AF) patients is ideally based on individual atrial remodeling. Electrical remodeling is believed to influence the outcome of direct current cardioversion ...
Interaction between cardiac and ventilatory timing during sleep
Cardioventilatory coupling is the temporal alignment between inspiratory onset and preceding heart beat, and is a determinant of ventilatory timing. Although investigated in anaesthetised and resting individuals, as well ...
Extended Care Paramedic clinical guideline compliance, does it have potential for harm?
Background
Extended Care Paramedic (ECP) practice is aimed at managing more patients at home or in the community under a delegated scope of practice applying pre-determined clinical guidelines. These clinical guidelines ...
ECG-based Risk Stratification of Ventricular Arrhythmia in Implantable Cardioverter Defibrillator (ICD) Patients
Aim: Implantable cardioverter defibrillators (ICDs) are life-saving devices invented in the 20th century that are now the standard of care for patients at high risk of ventricular arrhythmia, largely defined by either ...