The placenta is a crucial element of human life. It sustains and enables the development from a small group of cells to a whole organism. The placenta is a unique organ that fulfils multiple roles, from delivery of oxygen ...

Mood disorders such as Major Depressive Disorder and Bipolar Disorder are devastating burdens upon sufferers, their families and society as a whole. Despite their high prevalence and socioeconomic impact, understanding the ...

Methylation of DNA molecules is a fundamental mechanism for regulating gene function that is prevalent in all vertebrates. Although, the role of DNA methylation is well recognised in the disease context, the knowledge of ...

Gout was historically known as the king of diseases and disease of kings, reserved for those of wealthy, extravagant lifestyles. Far from being resigned to history books, gout is on the rise worldwide and in New Zealand – ...

Detection of nucleotide sequence variations in patients of some diseases, provides strong evidence as to which genes and regulatory elements play a critical role in vivo. Acute Myeloid Leukaemia (AML) is a fast acting blood ...

Two-thirds of human breast carcinomas test positive for oestrogen receptor α (ERα), which predominantly mediates oestrogenic actions in the normal breast as well in breast tumour cells. Treatment of hormone-sensitive tumours ...

The incidence of childhood acute lymphoblastic leukaemia (B-ALL) has increased since 1950s worldwide. The disease affects young children and it has physical and psychosocial impacts on children and their families. Different ...

Cancer is currently the leading cause of death in New Zealand, accounting for 30% of all deaths in 2010. Due to factors such as an ageing population and poor lifestyle choices, the incidence and mortality of this disease ...

Embryonic stem cells are pluripotent; they have the ability to form any cell type of the developing embryo. Due to their pluripotent nature there is a strong interest in understanding the biology of embryonic stem cells. ...

Colorectal cancer (CRC) is an insidious disease, responsible for almost 700,000 deaths annually worldwide. The incidence of CRC in New Zealand is more than double the world average, at 48.1 and 36.7 cases per 100,000 ...