Ubiquitylation, one of the most abundant post-translational modification in cells, is regulated by a cascade of enzymes (E1, E2 and E3 ligases). E3 ligases, along with their partner E2 enzymes, catalyse the final step of ...

Many clinically relevant bacteria use a population-dependent communication network - known as quorum sensing - to regulate the processes essential for the establishment of infections. Quorum sensing enables pathogens to ...

Pseudomonas aeruginosa requires iron for growth and metabolism, but is able to grow in environments where bioavailable iron is scarce. As such, the bacteria must scavenge iron from their environment using a variety of iron ...

Human-induced climate variability can subject global regions to water scarcity, prompting widespread crop failure. This calls for innovations that preserve global food security that do not further contribute to climate ...

Triple-negative breast cancer (TNBC) accounts for 10-20% of primary invasive breast cancer diagnoses, globally. With a higher risk of developing visceral and brain metastasis than other breast cancer subtypes, and limited ...