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Roles of phosphate-binding proteins in the Pst1 and Pst2 phosphate uptake systems of Synechocystis sp. PCC 6803
The uptake of phosphate from the environment is an important process for all organisms including cyanobacteria. Phosphate is a fundamental component of DNA, RNA, and ATP, which are integral for cell survival. The uptake ...
Regulation of the E3 Ligase Activity of Human Cellular Inhibitor of Apoptosis Proteins
Post-translational modifications serve to regulate the function, activity, abundance or cellular localisation of proteins in a dynamic and timely manner. One form of such modifications involves the covalent attachment of ...
Endometrial Cancer and Copy Number Variation
Endometrial cancer is the most common gynaecological cancer in New Zealand and the incidence is increasing as the population ages. Genetic predictors of endometrial cancer risk that allow early detection of the disease are ...
Structure and Function of the Psb27 subunit of Photosystem II
Photosystem II is a large protein complex that catalyses the light-driven oxidation of water. The biogenesis of Photosystem II is a regulated process that involves transient interactions between Photosystem II and dedicated ...
Genomic and transcriptomic associated studies in colorectal cancer
Colorectal cancer (CRC) is proposed to originate through three major molecular pathways, chromosomal instability (CIN), microsatellite instability (MSI) and the CpG island methylator phenotype (CIMP). Many studies have ...
The effect of riboceine on lipoprotein(a)
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. Atherosclerosis is characterized by the progressive formation of lipid plaques within blood vessel walls which eventually occlude the vessel ...
The Role of Type IV Pili of Synechocystis sp. PCC 6803 in Extracellular Electron Transfer
The objective of this research was to determine whether the Type IV pili of Synechocystis sp. PCC 6803 are involved in electron donation to the extracellular environment. In conjunction with the current theories and published ...
Divergent proteolysis of anti-sigma proteins controls cell-surface signalling in Pseudomonas aeruginosa
In cell-surface signalling pathways, the binding of an iron chelate to a specific outer membrane receptor induces gene expression in the cytoplasm via extra-cytoplasmic function sigma proteins. In these pathways gene ...
Regulatory Mechanisms Modulating the Co-Expression of ESR1 and Three Upstream Genes in Breast Cancer
Breast cancer is the most prevalent form of cancer diagnosed in women with oestrogen receptor α (ERα) positive breast cancers accounting for approximately 80% of all malignancies. Several genome wide association studies ...