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Thesis - Honours
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(Thesis, Bachelor of Medical Science with Honours, 2017)In many countries, including New Zealand, the caesarean delivery rate far exceeds the current WHO recommendation of 10-15% of live births. This is causing concern amongst a number of parties. One of the explanations for ... -
(Thesis, Bachelor of Medical Science with Honours, 2017)Cytosine methylation, normally found on cytosine residues adjacent to guanine (i.e., a CpG dinucleotide), is one means by which long-term gene repression occurs. Immediately after semi-conservative DNA replication, CpG ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2017)Many sexual dimorphisms that exist in the brain develop in the postnatal period. For males, this is when testosterone levels are minimal and anti-Müllerian hormone (AMH) is elevated. Testosterone requires the enzyme aromatase ... -
(Thesis, Bachelor of Radiation Therapy with Honours, 2017)Radiation skin reactions are a common side effect of radiation therapy and can be distressing and painful for patients. Head and neck cancer patients receive a high dose of radiation to the skin and are therefore at high ... -
(Thesis, Bachelor of Medical Science with Honours, 2017)Background: Recent years have seen anti-vascular endothelial growth factor (VEGF) agents revolutionize the treatment of wet age-related macular degeneration (AMD). To ensure optimal outcomes for this time-sensitive ...
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(Thesis, Bachelor of Radiation Therapy with Honours, 2017)Prostate cancer affects more than 3000 New Zealand men each year. Many of these men receive a complex type of radiation treatment which requires patients to have a full bladder and empty rectum to aid in the accuracy of ... -
(Thesis, B.A. (Hons.), 1979)The aims of this study are two-fold. First, to reach an understanding of the swagger, his lifestyle, and his outlook on life. And second, to investigate the relationships between the swagger and various groups in New Zealand ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2017)Human skeletal mass and strength increase from birth until ~35 years of age, thereafter a decline in mass and strength occurs in a process called sarcopenia. Beyond 60 years of age muscular weakness falls to a point where ...
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(Thesis, Bachelor of Arts (Honours), 2003)The Home Science Extension Service (HSES) of the Otago University was established in 1929. The Service intended to remedy a lack in the educational facilities available for rural women. The HSES developed from the example ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Release of Ca2+ from the sarcoplasmic reticulum (SR), mediated by the activation of the ryanodine receptor (RyR2), initiates myocardial contraction. This process of Ca2+-induced Ca2+ release is confined within a 20 nm ...
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(Thesis, Bachelor of Medical Science with Honours, 2016)Vitamin D therapy is commonly prescribed for people with chronic kidney disease to improve biochemical perturbations; however, evidence of effects on patient-centred outcomes such as mortality, cardiovascular events and ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Each year there are approximately 2.9 million joint replacement surgeries performed worldwide. Great efforts have been made to reduce infection rates in these replacements in the past and yet these rates have not decreased ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)The development of a positive energy balance occurs during pregnancy to support the growth of fetal and maternal tissues, and to increase energy stores in preparation for the metabolic demands of lactation. Leptin levels ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Schizophrenia is a debilitating chronic mental disorder with prominent frontal and hippocampal dysfunction. While the exact cause of schizophrenia is poorly understood, a number of factors, including neurodevelopmental ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Prolactin signalling through the prolactin receptor plays a significant role in many physiological processes. The diverse biological functions attributed to prolactin are largely dependent on the distribution of its receptor. ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Triple-negative breast cancer (TNBC) is an aggressive disease subtype with no current targeted systemic therapies due to a lack of actionable molecular targets. Efforts to identify therapeutic targets in TNBC have revealed ...
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(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Throughout the human female menstrual cycle, the endometrial lining of the uterus transitions from a non-receptive proliferative state to a receptive secretory state. This transition is required to prepare the endometrium ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Exercise reduces the risk of breast cancer development, and improves survival in breast cancer patients. However, the underlying mechanisms of this protective effect remain to be fully elucidated. It is unclear whether ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Abnormal mRNA splicing can disrupt gene function and influence the course of disease. Analysis of abnormal splicing is an important part of determining whether a particular genetic variant found in the population is ... -
(Thesis, Bachelor of Biomedical Sciences with Honours, 2016)Tuberculosis (TB) is a pulmonary disease caused by Mycobacterium tuberculosis, which killed 1.5 million people in 2014. The current TB vaccine, live attenuated Mycobacterium bovis bacille Calmette Guérin (BCG), effectively ...
