Background: Atopic dermatitis (AD) is a chronic skin condition characterised by the development of pruritic and inflamed lesions. One key component of AD pathogenesis is a cutaneous hyper-reactivity to allergens influenced ...

Transplantation of resident cardiac stem cells (CSCs) to the injured myocardium presents the potential to improve functioning of the diabetic heart in patients post-myocardial infarction. However, this therapy is not ...

Background Both NMSC and IBD primarily manifest in the Caucasian population. Given the predominance of Caucasians in the New Zealand population, and New Zealand’s specific latitude and ozone layer depletion, it is not ...

The Minimally Conscious State is a relatively new state, defined in order to separate patients who show signs of conscious awareness from those who are otherwise vegetative. Extensive research in this area has allowed for ...

Portimine is a bioactive compound recently isolated from the marine dinoflagellate Vulcanodinium rugosum. It is a member of the fast acting class of toxins called cyclic imines, which are typically lethal to mammals at low ...

The epithelial sodium channel (ENaC) is a protein located at the apical membrane of polarised epithelial cells, primarily expressed in the epithelia of the gastrointestinal tract, lungs and kidney. ENaC's main function is ...

Background: Given the discovery of cancer stem cells (CSCs) within haematological and solid tumours and the expression of primitive markers by infantile haemangioma, it was hypothesised that a CSC population would also be ...

Introduction Type 1 Diabetes Mellitus (T1DM) is a chronic life-long condition that commonly presents in children and adolescents. It is a condition that requires close monitoring, as poor management may lead to severe ...

Chronic fatigue syndrome / Myalgic encephalomyelitis (CFS/ME) is an unexplained chronic multi-system illness, which leads to a lifetime of impairment. Symptoms indicative of the disease include immunological dysregulation, ...

Sex determination and differentiation is an essential process all mammals must undergo to reproduce. This process in mammals is initiated through the development of a bipotential tissue, the urogenital ridge (UGR), which ...