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dc.contributor.authorGale, Christopher
dc.contributor.authorGlue, Paul
dc.contributor.authorWilkinson, Sam
dc.contributor.authorMcMurdo, Maave
dc.contributor.authorRapsey, Charlene
dc.contributor.authorCoverdale, John
dc.contributor.authorGuaiana, Giuseppe
dc.date.available2013-12-11T22:44:10Z
dc.date.copyright2013
dc.identifier.citationGale, C., Glue, P., Wilkinson, S., McMurdo, M., Rapsey, C., Coverdale, J., & Guaiana, G. (2013). Influence of covariates on treatment outcome in placebo-controlled trials of benzodiazepines in GAD. Presented at the Mental Health Research -- the Whole Picture. The Australian Society for Psychiatric Research (ASPR) 2013 Conference.en
dc.identifier.urihttp://hdl.handle.net/10523/4525
dc.descriptionThere was a variation in the subject and title from abstract submission to poster with the poster concentrating far more explicitly on modelling the causation of heterogeneity within the database of RCTs.en_NZ
dc.description.abstractBenzodiazepines are commonly used for anxiety disorders, but there is a lack of systematic reviews relating to their safety and efficacy. A Cochrane Review is in preparation comparing beizodiazepines with placebo and preliminary data indicates that benzodiazepines have a significantly higher response rate and a significantly lower drop-out rate, but at the cost of more side effects. One of the issues is that there is a moderate to high rate of heterogeneity, with I-squared values estimated at between 20% (for side effects)to 91% (for HAM-A). We will be presenting sensitivity analyses of these results, looking at the year of publication, diagnostic criteria, dose effects, and baseline severity.en_NZ
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen_NZ
dc.relation.urihttp://www.aspr2013.com.au/en_NZ
dc.rightsAttribution-ShareAlike 3.0 Unported*
dc.rights.urihttp://creativecommons.org/licenses/by-sa/3.0/*
dc.subjectBenzodiazepineen_NZ
dc.subjectPlaceboen_NZ
dc.subjectSeverityen_NZ
dc.subjectGeneralized Anxiety Disorderen_NZ
dc.subjectMeta analysisen_NZ
dc.titleInfluence of covariates on treatment outcome in placebo-controlled trials of benzodiazepines in GADen_NZ
dc.title.alternativeRe Benzodiazepines safe and effecacious in Generalized Anxiety Disorder? A meta-analysis aganist placeboen_NZ
dc.typeConference or Workshop Item (Poster)en_NZ
dc.date.updated2013-12-11T04:22:51Z
otago.schoolDepartment of Psychological Research, Dunedin School of Medicineen_NZ
otago.schoolMenninger Department of Psychiatry, Baylor School of Medicine,en_NZ
otago.schoolWestern Univeristyen_NZ
otago.bitstream.startpage142en_NZ
otago.openaccessOpen
dc.description.refereedPeer Revieweden_NZ
otago.event.placeMelbourne, Victoriaen_NZ
otago.event.titleMental Health Research -- the Whole Picture. The Australian Society for Psychiatric Research (ASPR) 2013 Conference.en_NZ
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Attribution-ShareAlike 3.0 Unported
Except where otherwise noted, this item's licence is described as Attribution-ShareAlike 3.0 Unported