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dc.contributor.advisorChisholm, Alexandra
dc.contributor.advisorSchultz, Michael
dc.contributor.authorHarvie, Ruth
dc.date.available2014-07-24T03:52:33Z
dc.date.copyright2014
dc.identifier.citationHarvie, R. (2014). A reduction in FODMAP intake correlates strongly with a reduction in IBS symptoms – The FIBS study. (Thesis, Master of Science). University of Otago. Retrieved from http://hdl.handle.net/10523/4927en
dc.identifier.urihttp://hdl.handle.net/10523/4927
dc.description.abstractBackground: Irritable Bowel Syndrome (IBS) affects 7-10% of the population. Patients have identified that food is a trigger for their symptoms. There is emerging evidence that a diet low in fermentable oligosaccharides, monosaccharides, disaccharides and polyols (FODMAP) is beneficial. This Randomised Controlled Trial (RCT) aimed to compare symptom severity and quality of life of participants following a low FODMAP diet and those following their customary diet at three months. The hypothesis was that a reduction in dietary FODMAP molecules would cause a reduction in symptom severity and an improvement in quality of life in participants with IBS. Methods: Participants with IBS according to Rome III criteria were recruited from gastroenterology outpatients, general practice and through advertising in a community newspaper. Participants completed the IBS SS (IBS symptom severity scoring system,0- 500 points), IBS QoL (IBS quality of life questionnaire, 0-100) and a FODMAP specific food frequency questionnaire at baseline and three months. They were randomised to either education with the dietitian on a low FODMAP diet or a waiting list control. Results: Out of 117 screened patients, 50 participants were recruited for the study, 32 of whom had diarrhoea predominant IBS. In the intervention group (n=23) there was a statistically significant reduction in IBS SS from 275.6 (±63.6) to 128.8 (±82.5) (p<0.0001) which remained significant when controlling for the reduction in the control group (n=27) (p=0.002). There was also a significant improvement in the IBS QoL in the intervention group from 68.5 (±18.0) to 83.0 (±13.4) (p<0.0001). This remained statistically significant when controlling for the change in the control group (p<0.0001). There was a statistically significant relationship between the reduction in FODMAP intake and the reduction in IBS SS score (p=0.02). There was no difference in bloating and the severity of pain when compared to the control group but there was a significant reduction in the frequency of pain when compared to the control group (p<0.0001). The low FODMAP diet consumed by participants was nutritionally adequate. Conclusion: This study demonstrated that a low FODMAP diet reduced symptom severity and improved quality of life in participants with IBS while ensuring a nutritionally adequate diet.
dc.language.isoen
dc.publisherUniversity of Otago
dc.rightsAll items in OUR Archive are provided for private study and research purposes and are protected by copyright with all rights reserved unless otherwise indicated.
dc.subjectFODMAP, IBS, irritable bowel syndrome
dc.titleA reduction in FODMAP intake correlates strongly with a reduction in IBS symptoms – The FIBS study.
dc.typeThesis
dc.date.updated2014-07-23T23:29:46Z
dc.language.rfc3066en
thesis.degree.disciplineHuman Nutrition
thesis.degree.nameMaster of Science
thesis.degree.grantorUniversity of Otago
thesis.degree.levelMasters
otago.interloanno
otago.openaccessAbstract Only
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