• The Health Impacts of Increasing Social Inequality in Late Prehistoric Northeast Thailand 

  Ward, Stacey Maree

  Evidence for increasing social inequality and a concurrent health deterioration has been observed in Iron Age (420BCE-500CE) northeast Thailand. Inequality is commonly considered to be represented by variations in quantities ...

• Cold and Crowded - The Early Childhood Education Environments Study 

  Bedford, Mike

  Background In recent decades New Zealand has seen a growth in the use of childcare as a weekday living environment for children under five years old, with an increasing proportion of children attending, and children ...

• Clinical and Surgical Anatomy of the Ligament of the Head of Femur 

  Perumal, Vivekanandan

  The ligament of the head of femur (LHF), or ligamentum teres, is an intra-articular ligament of the hip joint, running between the transverse acetabular ligament (TAL) of the hip and the fovea capitis femoris (FCF) on the ...

• Examining fatigue and performance in critical care clinicians 

  Myers, Julia Anne

  Background: Fatigue related to sleep deprivation has a degrading effect on human performance. In critical care health settings this represents a potential hazard to the safety of patients. This thesis aimed to identify and ...

• Toll like receptor signalling in human colonic organoids 

  Samuel, Gaurav

  Three-dimensional primary cultures of colonic epithelium, or colonic organoids, are thought to be a suitable culture system to investigate the properties of human intestinal epithelium and its interaction with commensal ...

• Assessment of central pain mechanisms: generating knowledge and resources for translation into clinical practice 

  Alqarni, Abdullah Mohammad A

  Background: Musculoskeletal (MSK) disorders are the second most common cause of disability. Persistent MSK pain has been associated with altered central pain mechanisms (CPMs), particularly somatosensory abnormalities. In ...

• Genome-Wide DNA Methylation in Polycystic Kidney Disease 

  Bowden, Sarah

  Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a heritable renal disease that causes the enlargement of kidneys due to the bilateral development of fluid-filled cysts. This results in end-stage kidney disease in ...

• Investigation of Several Compounds for the Treatment of Autosomal Dominant Polycystic Kidney Disease 

  McDougall, Lorissa

  Polycystic kidney disease (PKD) is a leading cause of kidney failure, and one of the most prominent rare hereditary diseases in New Zealand, as well as globally. The autosomal dominant form of this disease (ADPKD) has a ...

• Proceedings of the Health Professional Education Research Symposium 2017 

  Anakin, Megan Grayce

  This symposium was the first of its kind at the Dunedin School of Medicine. It was intended to provide a welcoming and supportive environment. To promote research and scholarship into health professional education at the ...

• Health journeys of Pacific children aged 10-14 years with mental health conditions in New Zealand: Evidence from the New Zealand Integrated Data Infrastructure 

  Prescott, Lesieli E.

  In New Zealand (NZ), young Pacific people are overrepresented among those experiencing mental health conditions (MHC) compared to young people of other ethnicities. Despite this, little is known about the possible determinants ...

• The use of technology in supporting goal setting in rehabilitation in adults: Protocol for a scoping review 

  Strubbia, Carla; Levack, William M.M; Grainger, Rebecca; Takahashi, Kayoko; Tomori, Kounosuku

  Background: Goal setting is considered an essential component of any rehabilitation programme. However, health professionals can struggle to involve patients in the goal selection process to the extent that they think is ...

• Exergaming to improve balance and decrease the risk of falling in individuals with knee osteoarthritis 

  Manlapaz, Donald

  Background: The benefits of exercise to improve balance and reduce the risk of falls is well-recognised in the older-adult literature. However, little attention is paid to people with osteoarthritis (OA) of the knee. While ...

• Characterisation of genes involved in exopolysaccharide biosynthesis and transport in the Mesorhizobium loti strain R7A 

  Fowler, Bjorn

  Rhizobia are bacteria that are important in fixing gaseous nitrogen into a plant-available form via a symbiotic interaction with leguminous plants. In order for this to occur, the legume and the rhizobia must communicate ...

• High Altitude Medicine: Understanding the Mechanism of Acute Mountain Sickness 

  Barclay, Holly Kate

  The present study was undertaken to determine the integrative physiology behind acute mountain sickness (AMS) susceptibility. We compared the respiratory, cardiovascular, renal and cerebrovascular responses to acute ...

• Improving the assessment process for patients presenting with acute (non-traumatic) abdominal pain to the general surgery department. 

  de Burlet, Kirsten Juliette

  Background Abdominal pain is a very common but also challenging presentation to general surgery. A number of implementations have been introduced to improve the diagnostic process. These include: ED 4-6 hour targets, acute ...

• Bioavailability and biological effects of isothiocyanates from broccoli sprout powder 

  Zawari, Masuma

  Broccoli sprout powder (BSP) is a rich source of glucosinolates that can be hydrolysed to isothiocyanates by enzyme myrosinase when the powder comes into contact with water. The major isothiocyanate produced in broccoli ...

• Slow dissolving inhalable dry powders for treatment of pulmonary tuberculosis 

  Eedara, Basanth Babu

  Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, which mainly affects the lungs. The current treatment by the oral or/and parenteral route of administration requires very high doses of the ...

• Understanding azathioprine metabolism using a systems pharmacology approach 

  Siripuram, Vijay Kumar

  Quantitative systems pharmacology (QSP) modelling, being an integral part of pharmacometrics, is attracting a great amount of attention in drug development and clinical therapy as QSP models are used to identify drug targets ...

• Regulation of Corticotropin-Releasing Hormone Neuron Activity by Noradrenergic Stress Signals 

  Gouws, Julia

  The stress response is crucial for allowing adaptation to an ever-changing external environment. The neuroendocrine stress response is controlled by corticotropin-releasing hormone (CRH) neurons located within the ...

• B-Type Natriuretic Peptide and Novel Cardiac Ultrasound in Very Preterm Neonates: Potential Markers for the Detection of Pulmonary Hypertension and for Risk Stratification 

  Harris, Sarah Louise

  Very premature birth causes an interruption of cardiorespiratory development. Successful pulmonary adaptation requires synchronous development of alveoli and pulmonary capillary networks. Very premature birth threatens ...

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