• The Oral Health Status of New Zealand Defence Force recruits and officer cadets. 

  Naysmith, Kate Elizabeth

  Aims The aim of this study was to investigate the oral health status of all new recruits and officer cadets entering the New Zealand Defence Force (NZDF) over a one-year period. The second aim was to investigate differences ...

• A socio-spatial analysis of pedestrian falls in Aotearoa New Zealand 

  Watkins, Alison; Curl, Angela; Mavoa, Suzanne; Tomintz, Melanie; Todd, Verity; Dicker, Bridget

  This report summarises the results of a study undertaken in 2019 to examine the built environment around the location of pedestrian falls in New Zealand using existing spatial data. Please see the publisher link for the ...

• Cognitive impairment and conversion to dementia in Parkinson's disease: an imaging study of amyloid PET and diffusion MRI 

  Stark, Megan Rebecca

  Objective To investigate the association between amyloid deposition or white matter degeneration with cognitive impairment and conversion to dementia in Parkinson’s disease (PD). Background Cognitive decline and ...

• Evaluation of intranasal particulate strategies to enhance the delivery of anti-seizure therapeutics to the brain 

  Prentice, Richard Neil

  Epilepsy is a common and serious neurological disorder to which a high proportion of patients continue to be considered “drug-resistant” despite the availability of a host of anti-seizure drugs. Investigation into new ...

• Crohn's disease: an in vitro analysis of T lymphocyte function and response to commensal microbes 

  Angus, Hamish Callum Keith

  Inflammatory bowel disease is a chronic, relapsing inflammation of the intestine. Approximately 0.5% of the western world is estimated to suffer from the disease. Crohn’s disease, a type of inflammatory bowel disease, ...

• MARS molecular imaging: Potential clinical utility of spectral photon-counting computed tomography integrated with nanoparticle technology 

  Lowe, Chiara Denise

  The aim of the research documented in this thesis was to investigate molecular imaging using a MARS spectral scanner. This scanner is a photon-counting computed tomography (CT) system that simultaneously measures 5-8 ...

• New Zealand’s vocational Rural Hospital Medicine training program: the first ten years 

  Blattner, Katharina; Miller, Rory; Lawrence-Lodge, Rachael; Nixon, Garry; McHugh, Patrick; Pirini, Joel

  Aims: The Rural Hospital Medicine Training Programme (RHMTP) was established in 2008 to develop NZ’s rural hospital medical workforce. This study evaluates the RHMTP’s first ten- year outcomes. Methods: A mixed-methods ...

• Novel drug development for KRAS-mutated non-small cell lung cancer 

  Shakil, Md Salman

  Lung cancer is the leading cause of cancer-related death among both men and women and non-small cell lung cancer (NSCLC) accounts for 85 to 88% of all lung cancer cases. In NSCLC, kirsten rat sarcoma (KRAS) viral oncogene ...

• The use of child oral-health-related quality of life measures in a randomised control trial of the Hall crown technique in a primary care setting 

  Lloyd, Helen Margaret

  The first aim of this thesis was to analyse the health-related (HRQoL) and oral-health-related quality of life (OHRQoL) information collected during the clinical trial of the Hall technique, to determine whether there were ...

• Protein discovery platform using deer antler as a model of mammalian regeneration 

  Dong, Zhen

  The ability to activate and regulate stem cells during wound healing and tissue regeneration is a promising field which could bring innovative approaches into regenerative medicine. The regenerative capacity of invertebrates ...

• The treatment of obesity in children and adolescents 

  Adams, Judith

  The main reason why the rising prevalence of childhood obesity is an important public health issue is that obese children are likely to become obese adults at high risk of developing diabetes and cardiovascular disease and ...

• Young People’s Sexual and Reproductive Health 

  Adams, Judith

  Having sex for the first time is a major milestone in life that almost everyone reaches. In New Zealand, around 37% of secondary school students have had sex by the age of 16 years and around 46% by the age of 17 or more.1 ...

• Fetal alcohol spectrum disorder 

  Adams, Judith

  There is substantial evidence from both observational studies of humans, and experimental studies in animals, that fetal alcohol exposure can cause physical malformations, growth retardation and brain damage.1-5 Alcohol ...

• Factors that influence inequity of oral health in New Zealand and what we can do about them 

  Beckett, Deanna M; Meldrum, Alison M

  Dental caries has been identified by the New Zealand (NZ) Ministry of Health (MoH) as the country’s most prevalent chronic disease.1 Dental diseases of the oral cavity include, but are not limited to, dental caries, ...

• Making health easier: Reducing inequalities in child health through addressing low health literacy 

  Adams, Judith

  Keeping their children healthy and safe is one of the most important responsibilities parents and caregivers have. It requires knowledge and skills that are acquired in a number of ways: from families and friends, through ...

• The determinants and consequences of overweight and obesity 

  Adams, Judith

  According to the World Health Organization, childhood obesity is one of the most serious public health challenges of the 21st century.1 Over the past thirty to forty years there has been a marked increase in the prevalence ...

• E-cadherin and APC in early-onset colorectal cancer 

  Aitchison, Alan

  Colorectal cancer (CRC) is a considerable health burden being the second highest cause of cancer deaths globally. While overall cases of CRC have been declining worldwide, there has been an increase in the incidence of the ...

• Management of Osteoarthritis in the NZ Public Health System 

  Abbott, J. Haxby; Wilson, Ross; Chua, Jason

  Osteoarthritis (OA) is a leading cause of health losses and costs in NZ. The burden of OA is rising as a result of population ageing, rising obesity, increasing injury rates, and earlier onset of disease. The New Zealand ...

• Modulation of interhemispheric inhibition and its effect on stroke recovery in the rat 

  Melchers, Rose Joy

  Rationale: Residual disability following stroke is a significant challenge for patients and the healthcare system, both in New Zealand and worldwide. Poor recovery from motor cortex (M1) stroke has been associated with an ...

• Assessing medication appropriateness in older adults and recommending therapeutic alternatives in individuals with dementia 

  Bala, Sharmin Sarosh

  Older adults comprise a significant proportion of the population of New Zealand (NZ) and are known to be prescribed the highest number of medications. Several medications have to be prescribed with caution in older adults ...

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