Division of Health Sciences Departments
The Division of Health Sciences will provide New Zealand society and other communities with a highly qualified workforce in the health professions. The Division will promote health and health care through basic and applied research and academic and professional leadership. This will be achieved through research-based undergraduate, postgraduate and professional academic programmes of international standard in the health sciences and related sciences.
Sub-communities within Division of Health Sciences Departments
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Faculty of Dentistry [200]
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University of Otago, Christchurch School of Medicine and Health Sciences [245]
Christchurch School of Medicine and Health Sciences -
University of Otago, Wellington [251]
Wellington School of Medicine and Health Sciences
Collections in Division of Health Sciences Departments
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Bioethics Centre [50]
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School of Pharmacy [89]
Recent Deposits
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Atherogenic Index In Plasma and Risk of Cardiovascular Events
As dyslipidaemia is a prominent CVD risk factor, improvements in its management are crucial, as dyslipidaemia (quantified by hypercholesterolemia and treated with statins), incompletely addresses the residual CVD risk ... -
Arterial Hypertension. Consume Carbon Monoxide?
Epithelial sodium channels (ENaC) are generally responsible for the passive movement of sodium ions through the apical cell membrane of salt absorbing epithelia. Canonical ENaC is composed of three homologous subunits, ... -
Characterisation of Arcuate Nucleus Projections to the Paraventricular Nucleus of Thalamus
The metabolic state (fed or hungry) has been shown to influence varying responses to food-associated cues. Recent studies reveal that the paraventricular nucleus of the thalamus (PVT) may play a critical role as it receives ... -
A Novel Oocyte Cryopreservation Method using High Pressure Freezing
Oocyte cryopreservation (egg freezing) involves freezing a female’s oocytes in order to preserve her fertility. These oocytes can later be thawed and fertilised in vitro when she is ready to begin fertility treatment. Women ... -
Bacterial regulation of early activation of mucosal-associated invariant T (MAIT) cells
Mucosal-associated invariant T (MAIT) cells are a population of CD8+ innate-like T cells that play an important role in the immune response to bacterial infections. Being characterised by the expression of a unique ... -
The α-Adrenergic System and CaMKII in Diabetic Heart Disease
The relationship between diabetes mellitus and heart disease is widely documented, with heart disease being the main cause of mortality in diabetic patients. Diabetes impairs the autonomic nervous system, leading to an ... -
The Role of α-ENaC and δ-ENaC in Breast Cancer Cell Migration
Breast cancer is an important disease worldwide, primarily affecting women, and is the most common and deadliest form of female cancer. This is reflected in New Zealand’s population as breast cancer has high incidence and ... -
Candidate Compounds for the Chemoprevention of Hereditary Diffuse Gastric Cancer
Hereditary diffuse gastric cancer (HDGC) is a cancer syndrome caused by germline mutations in the tumour suppressor gene CDH1, which encodes the cell-cell adhesion protein E-cadherin. Mutations in CDH1 lead to increased ... -
Investigation into the Anticancer Mechanism of Action of Novel 4-Substituted Phenylthiazoles and Antihelminthic Benzimidazoles
Recently, two novel 4-substituted phenylthiazoles, D1 and D2, have been synthesised based upon the marine bacterial secondary metabolite anithiactin A/thiasporine C, and shown to be cytotoxic towards cancer cells below 100 ... -
Validation and Characterisation of Novel miRNAs Identified in the E15.5 Mouse Brain
MicroRNAs (miRNAs) are small noncoding elements that downregulate gene expression and play an important role in maintaining robust neurodevelopment. Since abnormal expression of miRNAs has been associated with disorders ... -
Bond strength of a direct composite resin to resin-matrix ceramic materials with four surface treatments
Background Aesthetic demands have popularized the use of dental ceramic and indirect composite resin materials in modern dentistry. The introduction of dental CAD/CAM technology expanded the use of these materials even ... -
Vital Bleaching (At-home, In-office, In-office + At home), Colour Change and Oral Health Related Quality of Life
Abstract Objectives This randomised clinical trial compared tooth colour change, participant satisfaction and Oral Health-Related Quality of Life (OHRQoL) following application of at-home, in-office and combined at-home ... -
BRAF mutations in ameloblastoma: Correlation with clinical and histopathological features and behaviour
Background: The invasive nature of ameloblastoma necessitates tumour-free surgical margins to minimise recurrence and thereby ensure improved prognosis. The vast majority of ameloblastomas originate centrally, and surgical ... -
Neuropilin-1 expression in the tumour microenvironment of oral squamous cell carcinoma
Background: Neuropilin-1 (Nrp-1) is a transmembrane glycoprotein involved in multiple biologic and pathologic processes including carcinogenesis. It is widely expressed in cancers where it has been correlated with poorer ... -
uORF-mediated translational regulation of drought stress response gene MASP1 in Arabidopsis thaliana
Human-induced climate variability can subject global regions to water scarcity, prompting widespread crop failure. This calls for innovations that preserve global food security that do not further contribute to climate ... -
Investigation into the relative location of filamin B and YB-1 in cell cycle progression
The cell cycle is a fundamental process in development and the maintenance of homeostasis. Various proteins regulate the cell cycle, such as Y-box binding protein -1 (YB-1). YB-1 transcriptionally regulates cell cycle ... -
Clinical guideline use and compliance: examining variation from the clinical pathway
Introduction Clinical guidelines are developed with the aim of optimising patient care and have been shown to improve both clinical outcomes and the care process. ‘Hospital HealthPathways’ are guidelines published for use ... -
Validation and Characterisation of Novel miRNAs Identified in the E15.5 Mouse Brain
MicroRNAs (miRNAs) are small noncoding elements that downregulate gene expression and play an important role in maintaining robust neurodevelopment. Since abnormal expression of miRNAs has been associated with disorders ... -
The role of O-GlcNAcylation in regulating the function and structure of cardiac ryanodine receptors
Diabetes mellitus is projected to be the leading cause of death worldwide by the year 2030 and has been linked to many cardiovascular disorders, which together are known as, diabetic heart diseases (DHDs). DHDs include ... -
Effect of WNT/β-catenin Signalling on T cells in Colorectal Cancer
Worldwide, colorectal cancer (CRC) is the fourth most common cancer and has the second highest mortality rate of any cancer. Only a subset of CRC patients respond to immunotherapies. This lack of response may be due to the ...