Browsing Division of Health Sciences Departments by Title
Now showing items 1019-1038 of 2217
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Identifying the functional role of miRNA-34a in diabetic cardiac stem cells
Transplantation of resident cardiac stem cells (CSCs) to the injured myocardium presents the potential to improve functioning of the diabetic heart in patients post-myocardial infarction. However, this therapy is not ... -
Identifying the fundamental elements of learning in a simulated clinical setting using a Delphi technique.
Identifying fundamental elements of learning in a simulated clinical setting using a Delphi technique. Name: Jessica Young1, Martyn Williamson1, Ben Daniel Motidyang2, Jim Ross1, Tony Egan1 Origin: 1University of ... -
Identifying the role of connexin 43 in transport of microRNAs
Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Present treatments for CVD rely heavily on surgical interventions and drug therapies that relieve symptoms rather than cure the disease. Therefore, ... -
Identity of FEZF2-Expressing Neurons in Layer 5 of the Adult Mouse Motor Cortex
For over a century the primary motor cortex (M1) has remained a research active area of the cerebral cortex. It is an intricately organised structure with billions of diverse neurons forming precise neuronal circuits ... -
Immediate Single Implant Restorations in Mandibular Molar Extraction Sockets
For the replacement of individual missing teeth, a paradigm shift is currently observed with immediate implant placement and/or restoration of incisor, canine and premolar sites of the aesthetic zone. In molar sites however, ... -
Immediate Single Implant Restorations in Mandibular Molar Extraction Sockets: A Four-Year Controlled Clinical Trial
Several systematic reviews and meta-analyses have clearly showed a lack of properly designed controlled clinical trials comparing the outcome of a combined immediate implant placement and loading protocol with that of ... -
Immediately placed single implants in the maxillary anterior zone: 5-year clinical study
Single implant crowns have become a popular treatment modality to replace a missing natural tooth. They have an excellent long-term success rate, especially when supported with a conventional placement and loading protocol. ... -
Immune Biomarkers to Identify Resilient and Susceptible Johne's Disease Phenotypes in Red Deer (Cervus elaphus)
Studies have identified breeds of farmed red deer (Cervus elaphus) that express polarised phenotypes for Resilience (R) or Susceptibility (S) to Johne’s disease, following natural infection with Mycobacterium avium subspecies ... -
Immune Markers of Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a rare, but fatal disease of the pulmonary arteries that evades early diagnosis. Although modern targeted therapies have improved symptoms and outcomes in PAH, lung transplantation ... -
Immune profiles in sheep following experimental infection with Mycobacterium paratuberculosis
Johne's disease in ruminants is caused by the pathogenic bacterium Mycobacterium avium subspecies paratuberculosis. An experimental infection model in sheep was developed as a prelude to the testing of new vaccines and the ... -
Immune Responses in Primary Oral Squamous Cell Carcinoma and Lymph Node Metastasis
Background: Oral squamous cell carcinoma (OSCC) develops in an immune cell-rich environment, where inflammatory cells in the tumour microenvironment establish an anti-tumour response by secreting pro-inflammatory cytokines. ... -
Immune suppression and cutaneous squamous cell carcinoma tumour biology
Cutaneous squamous cell carcinoma is a non-melanoma skin cancer that is among the most common cancers capable of metastasis. The majority of cutaneous squamous cell carcinomas (cSCCs) are easily treated by simple surgical ... -
Immunisation with chitosan hydrogel generates CD8+ memory T cells protective against tumour challenge
Vaccination is used in the prevention of disease around the world. Through activation of T and B cells, and subsequent generation of memory cells, long lasting protection against disease is given. The majority of vaccines ... -
Immunological and Biological Markers of Regression of CIN 2 in Women Under 25
Objective: This study discusses the need for a biomarker of regression of CIN 2 in women under 25, and aims to identify such a marker. Materials and methods: Women under 25 who were managed conservatively for CIN 2 at ... -
Immunological Parameters of Resistance and Susceptibility to Johne’s Disease in Red Deer (Cervus elaphus)
Resistance and susceptibility to infectious diseases are well-documented in a variety of host species. While environmental modifiers and pathogen virulence influence disease severity following infection, a major contributor ... -
Immunomodulation and Vaccination with RHDV VLP
Colorectal cancer (CRC) is an insidious disease, responsible for almost 700,000 deaths annually worldwide. The incidence of CRC in New Zealand is more than double the world average, at 48.1 and 36.7 cases per 100,000 ... -
Immunopathology of Omeprazole-Induced Acute Insterstitial Nephritis
Aim: The aim of this study was to define the nature of the inflammatory infiltrate that occurs with omeprazole-induced acute interstitial nephritis (AIN) and further to compare and contrast the histology of omeprazole-induced ... -
Impact of Dietary Fatty Acids on Neuronal and Metabolic Health
In the past decades, the worldwide prevalence of obesity has nearly trebled. This trend is mainly caused by the permanent availability of food, the consumption of a Western-style diet, and the sedentary lifestyle of our ... -
The impact of economic theory on the art of clinical practice : a study of science, meaning, and health
In being philosophically based this thesis is concerned with understanding the human condition with particular reference to matters of meaning and how these find expression in systems of government and social policy. ... -
Impact of G-quadruplex structures and DNA methylation on allelic drop-out during in vitro amplification of imprinted genes
Diagnostic testing for genetic disorders or techniques such as preimplantation genetic diagnosis (PGD) both require accurate PCR genotyping (1). The failure of amplification of one allele, referred to as allelic drop-out ...