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Electrophysiological Characteristics of Kisspeptin Neurons in the Hypothalamus of the Mouse
The gonadotropin-releasing hormone (GnRH) neurons are the principal neurons in a network within the hypothalamus that controls fertility in all mammals. GnRH neuron output is influenced by a wide range of neurotransmitters. ...
The role of yoga in the symptom management of musculoskeletal conditions
Background. Musculoskeletal conditions comprise a diverse group of disorders, united by a commonality of biopsychosocial symptoms including pain, functional disability, and decreased quality of life. Yoga is a popular form ...
Clinical measures of balance for people with cerebellar ataxia: Use and recommendations
This thesis aimed to recommend a core set of clinical measures for the assessment of balance of people with cerebellar ataxia. It comprised four studies: Narrative review, Systematic review, Delphi survey and Psychometric ...
Long peptide vaccines for the treatment of melanoma
Melanoma is the most serious form of skin cancer, with New Zealand having the world’s highest incidence rates. It is characterised by an aggressive clinical behaviour, associated with metastasis to distant organs and poor ...
The effect of alginate lyase on the antibiotic sensitivity of mucoid Pseudomonas aeruginosa biofilms
Bacteria are single celled organisms that can live together in communities called biofilms. These biofilms consist of a structural matrix consisting of polysaccharide gel secreted by the bacteria, with the bacteria living ...
Functional Analysis of Disease-Associated 3’ UTR Variants: the CXCL12β 3’ UTR G801A Polymorphism
In recent years, the previously neglected 3’ untranslated region (UTR) has gained recognition as a critical region in the regulation of gene expression. Numerous studies have been conducted on disease-associated 3’ UTR ...
The structure of the mucosal folds within the pancreaticobiliary junction
BACKGROUND: This investigation concerns a structure within the pancreaticoduodenal region of the body, known as the pancreaticobiliary junction (PBJ), which is formed from the convergence of the terminal common bile and ...
Reading the Bones: A Taphonomic Analysis of Lapita Mortuary Practices
People carrying the Lapita culture, which first appeared in the Bismarck archipelago c. 3300 BP, were the first colonists of Remote Oceania. While over 200 Lapita sites have been identified throughout the Pacific, very few ...
Agmatine and age-related cognitive decline
Declined learning and memory ability is common in aged individuals. Such age-related cognitive decline is associated with the dysfunction of the prefrontal cortex, hippocampus and its adjacent entorhinal, perirhinal and ...
Effect of aging on long-term potentiation-induced gene expression profiles in the hippocampus
Aging is characterized by an increased risk of cognitive deficits. It was shown using rodents that aging is associated with a significant reduction in the function of hippocampus, the brain structure important in forming ...