Division of Health Sciences Departments: Recently added
Now showing items 1-20 of 1851
-
Investigating the regulation of Arkadia activity in cells
Ubiquitylation is a post translational modification the regulates a wide variety of cellular processes. The attachment of ubiquitin onto a substrate requires the activity of three enzymes; E1, E2 and E3. As ubiquitylation ... -
The role of ascorbate in controlling hypoxia factors in renal cell carcinoma
Clear cell RCC (ccRCC) is the most common and also most aggressive RCC type harbouring alterations in the VHL tumour suppressor gene leading to uncontrolled accumulation of pro-survival hypoxia inducible transcription ... -
The threat to kill.
THE PURPOSE AND PLAN OF THIS THESIS It is considered that the neglected problem of homicidal threats is a subject not only of psychological interest but also of practical importance to the psychiatrist. The purpose of ... -
The advantages and disadvantages of introducing a funded HPV vaccine for boys aged between 9 - 20 years
Human Papillomavirus(HPV) vaccine has been internationally recognised to decrease the prevalence of HPV related diseases. Introduced to New Zealand with a female focus in 2008, the researcher of this study wanted to explore ... -
Osteoarthritis of the knee joint and hyperextension of the knee joint after stroke
Introduction: Some physiotherapists are reluctant to allow their patients to walk on a hyperextended knee after stroke in the unproven belief that it will precipitate the development of symptomatic osteoarthritis of the ... -
Evaluating environmental DNA (eDNA) metabarcoding as a method for monitoring biodiversity in marine ecosystems.
Halting current global biodiversity loss is important to maintain ecosystem functioning. To succeed in halting biodiversity loss, information is needed on community composition, abundance of species, and changes in these ... -
Is there leniency for female sexual offenders in sentencing decisions?
Current prevalence rates indicate that females are responsible for approximately 4%-5% of all sexual offences. Researchers examining court and sentencing outcomes for female sexual offenders (FSOs) have found that they may ... -
Investigating cellular remodelling events induced by the oncolytic Seneca Valley Virus
Cancer is a worldwide problem affecting millions of people. Typical cancer treatments are often very toxic and have a range of negative side effects. A new field of cancer research that may provide new cancer therapies is ... -
Quantifying global CG methylation in regenerative Zebrafish caudal fin and Xenopus tail buds.
Epigenetics is a control mechanism that creates stable alterations in gene expression thatdoes not require underlying changes in DNA sequence. One of the most iconic and prevalent epigenetic mechanisms involves CG methylation, ... -
Risk factors for venous thromboembolism
Background Many risk factors for venous thromboembolism have been identified, but two particular exposures - the use of combined oral contraceptives and long-distance air travel - have generated considerable concern in ... -
Sheep mandibular animal models for dental implantology research
This inquiry investigated the suitability of the jaw of domestic sheep as an animal model for dental implantology research. Initially, parameters for osseous healing of critical size defects (CSD) in the sheep mandible ... -
An investigation in the neuromodulation of olfactory function using non-invasive vagus nerve stimulation
In the existing literature, invasive direct vagus nerve stimulation (VNS) using high frequencies has shown to be effective in modulating the activity of the olfactory bulb in animal models. Under indirect vagus nerve ... -
Spray-dried powder particles for treating pulmonary tuberculosis
Background Tuberculosis (TB) is a major global health burden. Rapid emergence of drug-resistant TB has aggravated the current situation of global TB. High dose delivery of drugs to the lung using a dry powder inhaler (DPI) ... -
Formulation Strategies to Enhance Nose-to-Brain Delivery of Drugs
Delivery of drugs via the intranasal olfactory route is a non-invasive and practical method of bypassing the blood-brain barrier (BBB). However, targeted delivery and retention of drugs to the olfactory region is a significant ... -
Knowledge, attitudes and intentions of general practitioners and practice nurses and Christchurch and HPV and HPV vaccines
Background: Human papillomavirus (HPV) is a very common sexually transmitted infection (STI) and nearly all cervical cancers are causally related to infections by HPV. Gardasil®, a quadrivalent HPV vaccine, is now on the ... -
Spectroscopic investigation and quantitation of polymorphism and crystallinity of pharmaceutical compounds
Spectroscopy is increasingly used to investigate and monitor the solid state forms of pharmaceutical materials and products. Spectroscopy's speed, non-destructive sampling, compatibility with fibre optics and safety also ... -
Towards a deeper understanding of the polymorphic conversion of carbamazepine in aqueous suspension
Polymorphism can influence every aspect of the properties of a solid including the shelf life, dissolution rate, solubility, formulation properties and processing properties of a solid drug. A deeper understanding of ... -
Nutritional Factors in the Paleoepidemiology of Infectious Disease in the Ancient Atacama Desert
The adoption of agriculture in ancient human groups is thought to have resulted in a general decline in health, as evidenced by an increase in skeletal markers of infectious disease and nutritional stress in post-transitional ... -
Evaluation of the National Cervical Screening Program by calculation of the positive predictive value and standardized mortality rate
Cervical cancer is the 3rd commonest cancer occurring among women worldwide, behind breast and colorectal cancer. (Parkin et al. 1999) Screening via the use of cervical smears to detect preclinical disease has been successful ... -
Association of Polynesian-specific variants of PRPSAP1 and SLC22A3 genes with gout.
Gout is a complex disease caused by over-production and/or under-excretion of urate, which causes hyperuricaemia. This leads to urate deposition, and initiates the formation of monosodium urate (MSU) crystals in joints and ...