Division of Health Sciences Departments: Recently added
Now showing items 1-20 of 2549
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The Management of Osteoarthritis | Maimoatanga Kaikōiwi Research Programme, 2007-present
The research outputs featured in this abridged selection provide evidence regarding the burdent of osteoarthritis in the NZ adult population, and the effectiveness, cost-effectiveness, and stakeholder acceptability of ... -
Central Regulation of the Diabetic Heart
Cardiovascular diseases account for 80% of the premature mortality amongst individuals with Type 2 Diabetes Mellitus (DM). Diabetes is associated with detrimentally higher sympathetic drive to the heart and with disrupted ... -
A Probe for Conformational Change of Hsc70 in Mammalian Cells under Stress Conditions
Hsc70 is a constitutively expressed member of the heat shock protein family. It has an important role in proteostasis and can stabilise nonnative proteins before being further matured in refolding, disaggregation, and ... -
Psychological factors associated with pharmacist involvement in patient-centered services
Pharmacists are actively being encouraged to do more patient-centred activities like medicines management, primary care for common ailments, prescribing, and vaccination as their role evolves. However, the adoption of ... -
Genetic manipulation of Plasmodium cynomolgi as a model for investigating Plasmodium vivax drug resistance
Plasmodium vivax is the most widely distributed cause of human malaria, and thought to be the most difficult to diagnose and treat. Until recently this species has largely been neglected compared to the most significant ... -
Access to medicines and use of medicines by Māori with type 2 diabetes in Tairāwhiti
Type 2 diabetes and its associated co-morbidities have a significant impact on Māori and other indigenous populations. The prevalence of type 2 diabetes in Tairāwhiti was far greater for Māori than non-Māori (11% vs 4%). ... -
Inequalities in sustainable transport use in Aotearoa New Zealand: gender, intersectionality, and commuting using sustainable modes
Background: Sustainable transport (ST) offers significant public health benefit. Increasing ST-use, as an alternative to motor-vehicle transport, is a significant strategy for reducing/mitigating environmental damage. ... -
An In Vitro Comparison Study of Two Cell Therapies for Cardiac Repair
Cardiovascular disease continues to be the leading cause of death in New Zealand and throughout the world. Apart from orthotopic heart transplantation, no current treatment can prevent the progression of disease. Due to ... -
Motion measurement algorithms for MARS imaging
The goal of the MARS molecular imaging team is to advance medicine by researching, developing, and commercialising spectral CT systems. This thesis presents the work I performed to facilitate live imaging with MARS scanners. ... -
Strategies to enhance CAR T cell function in solid tumours utilising coding and non-coding genes
Cancer immunotherapy has emerged as an effective treatment to provide benefits to cancer patients. One of the main treatment modalities of cancer immunotherapy is the adoptive transfer of T cells with genetically engineered ... -
Development of hydrogel-based strategies for tissue vascularisation
The tissue engineering field and regenerative medicine has emerged as a promising strategy to overcome the lack of availability of organs and tissue grafts for transplantation. One of the main challenges in the field is ... -
Development and preclinical evaluation of an oral therapeutic colorectal cancer vaccine
Colorectal cancer (CRC) has become the second most common cause of cancer death worldwide, indicating the need for novel therapies to reduce mortality rates and the global burden of this disease. Therapeutic subunit vaccines ... -
Mechanisms of bactericidal action and β-lactam synergy by the zinc ionophore PBT2
The emergence and global spread of antimicrobial resistance (AMR) is an increasingly serious threat to human and veterinary medicine. Driven by the misuse and overuse of antibiotics, resistance to our antibiotic armoury ... -
Contested boundaries: E-scooter riders’ and pedestrians’ experiences of sharing space
Globally, e-scooters have become a popular mode of transport with the arrival of shared e-scooter services in cities and the availability of e-scooters for private purchase. E-scooters represent an exciting opportunity to ... -
Grafting purified cortical pericytes into mouse motor cortex
Brain regeneration through stem cell transplantation studies holds the potential to enhance functional recovery of the damaged brain. Most of the positive effects fostered by transplanted stem cells are believed to be ... -
Chromaffin Cell Ca2+-Responses in Rat Adrenal Medullary Slices
Adrenal medullary chromaffin cells undergo exocytosis of catecholamines to provide physiological and behavioural adaptations during stress. Several different stimuli are known to evoke catecholamine secretion from the ... -
Clinical anatomy of the neurofascial sheath
Background: The peripheral nerve blockade (PNB) and minimally invasive surgery are central to the “Fast Track Surgery” strategy which uses multimodal perioperative rehabilitation programs and aims to facilitate early ... -
Palatal periosteum-derived Mesenchymal stem cells in osteogenesis
Mesenchymal stem cells sourced from the palatal periosteum (PDCs) could be an alternative to using bone marrow aspiration procedures known to be associated with donor site morbidity. For safe use in human therapy, MSCs ... -
An Exploration of Mental Health Promotion in New Zealand: A Qualitative Study
Mental health promotion employs a strengths-based approach and focuses on promoting positive mental health. The current level of knowledge and reporting about mental health promotion efforts occurring in New Zealand is ...