Division of Health Sciences Departments: Recently added
Now showing items 1-20 of 1970
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The role of PsbX and PsbY in Photosystem II of Synechocystis sp. PCC 6803
Photosystem II (PS II) is the water-plastoquinone oxido-reductase responsible for splitting water in photosynthesis. The core of the enzyme is surrounded by 13 low-molecular-weight (LMW) proteins (<10 kDa). In this study, ... -
Complex Regional Pain Syndrome (CRPS) physiotherapy management: a cohort, observational, prospective, longitudinal study across the South Island of New Zealand
Physiotherapy management for CRPS is considered to be essential. However, there is a lack of validated evidence-based treatments. There is controversy between what treatment methods are safe or effective. Physiotherapy ... -
The impact of hepatic steatosis on liver circulation, transplantation, ischaemia-reperfusion injury and its relation with nitrous oxide
Obesity is now a major health threat in the developed world. To investigate the impact of obesity-induced steatosis on hepatic blood flow, portal venous and hepatic arterial blood flow were measured in the anaesthetized ... -
The Canterbury Ileal Pouch-Anal Anastomosis Study
Background and aim: Inflammatory bowel disease (IBD) is an increasingly prevalent chronic disease, frequently with an early age of onset and no cure. It is important to ascertain which treatments are effective and ... -
Shear Force Activation of the Epithelial Sodium Channel (ENaC): Role of the β- and γ-Subunits
Mechanotransduction describes the ability of a living organisms to sense mechanical forces that are caused through changes in the environment. It is a complex mechanism in which mechanical forces are converted into a ... -
BCG impact on Innate Lymphoid Cells: Determining the Site of Proliferation
Tuberculosis (TB) is an infectious lung disease that is a major cause of mortality, causing an estimated 1.7 million deaths globally per year. The current prophylactic vaccine used against TB, bacille Calmette Guérin (BCG), ... -
Making health equity count: Incorporating health equity for Māori into cost-utility analyses
Objective The New Zealand health system has a number of objectives including reducing disparities in health for Māori and improving total population health. Despite this there are stark inequalities in health status for ... -
Making health easier: Reducing inequalities in child health through addressing low health literacy
Background: Low health literacy is a major contributor to disparities in child health outcomes between different population groups and a powerful mediator of the social determinants of health. This review aimed to identify ... -
Child Poverty Monitor 2018: Technical Report
Each and every child has the right to grow up to be healthy, strong, well-educated and capable of contributing to their community and wider society, as demonstrated in every international agreement to recognise and protect ... -
Diet, Microbiota and Metabolic Health
Diabetes is one of the largest global health crises, affecting some 415 million adults worldwide, with type 2 diabetes mellitus (T2DM) accounting for at least 90% of all cases of diabetes. In line with international ... -
Application of pharmacometric methods to understand warfarin dose response
Existing warfarin dosing methods do not accurately predict warfarin maintenance doses for patients in the lower or upper quartile of dose requirements. It was argued that this is related to the use of the international ... -
Histories of Chest Pain: history of the presenting complaint as recorded by different health care providers of patients presenting to a rural hospital with suspected acute myocardial infarction
This thesis investigates how different health professionals record the history of the presenting complaint of patients with suspected acute myocardial infarction admitted to a rural hospital. Different health professionals, ... -
The role of Numb in honeybee ovary activation
Environmental signals in utero are throught to induce plastic changes to metabolism and gene regulation, causing diseases such as Type 2 Diabetes. For example, fetal undernutrition is associated with obesity, hyperglycemia, ... -
The role of the mTOR-Raptor complex in driving hyperuricemia-induced diabetes mellitus
Elevated serum uric acid (hyperuricemia) when left untreated can lead to a range of pathologies including gout, cancer and type 2 diabetes mellitus (T2DM). It has been shown that after three days of exposure to hyperuricemic ... -
Analysing components of the Torso-activation module: Do they pattern the end-terminal regions of two Hymenopteran insect species, Apis mellifera and Nasonia vitripennis?
This project sought to determine if components of the Torso-activation module pattern the embryonic anterior and posterior ends of the honey bee, Apis mellifera, and the parasitoid wasp, Nasonia vitripennis via a patterning ... -
Disarming tissue factor: generating a model tumour antigen
Coagulative abnormalities are a well-recognised feature of malignancy. The risk of developing thrombotic disorders is increased four-fold in cancer patients and more than six-fold higher in those receiving chemotherapy. ... -
Investigating Teixobactin Tolerance in Enterococcus faecalis
The rapid rise of antimicrobial resistance (AMR) poses a global threat to human health. Key to combating antimicrobial resistance will be to increase our understanding of how resistance develops. Conventional antimicrobial ... -
The presence of ∆133p53 and ∆40p53 in metastatic brain tumours: evidence for further enquiries
Metastatic brain tumours are becoming more prevalent as individuals with primary cancers receive improved treatment and live longer. These brain tumours are difficult to treat and are often left undiagnosed. This study ... -
Development of a local protocol and method to measure Beta-Cell Function in individuals with Pre-diabetes and Type 2 Diabetes
Type 2 diabetes mellitus (T2DM) is long-term metabolic disorder characterised by high blood glucose (BG), insulin resistance and poor insulin secretion. T2DM is preceded by pre-diabetes characterised by altered glucose ...