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dc.contributor.advisorCutfield, Nicholas
dc.contributor.advisorDawes, Patrick
dc.contributor.advisorDarlington, Cynthia
dc.contributor.authorTranter-Entwistle, Isaac Brian
dc.date.available2016-05-18T04:08:09Z
dc.date.copyright2016
dc.identifier.citationTranter-Entwistle, I. B. (2016). Vestibular Function in Vestibular Schwannoma (Thesis, Bachelor of Medical Science with Honours). University of Otago. Retrieved from http://hdl.handle.net/10523/6459en
dc.identifier.urihttp://hdl.handle.net/10523/6459
dc.description.abstractAbstract Introduction: Traditionally vestibular function has been assessed using caloric irrigations; new methods have failed to reach the same level of accuracy. Vestibular nerve dysfunction occurs with ‘acoustic neuroma’ or ‘vestibular schwannoma. Quantitative testing of hearing by audiometry is much more widely available than quantitative vestibular testing, although consideration of vestibular dysfunction is part of clinical management. Validation of a new method of quantitative vestibular function testing could lead to more widespread integration into clinical practice and affect decision making (i.e. timing of surgery) Methods: A non-blind observational cohort study was undertaken in 31 participants. Study endpoints were either one or two separate participant measures in March/April 2013 the September/October 13. All participants underwent caloric and head impulse testing with video-oculography, while 10 underwent audiometric assessment. Repeat testing was performed for 10 subjects, including additional cognitive. The primary outcome was vestibular function test measures. Results: Video head impulse was strongly correlated with calorics (p=0.01) and showed good sensitivity (80%) and specificity (70%). Dizziness Handicap Inventory showed no correlation with other vestibular function measures. Participants showed reduced cognitive function tested using the CANTAB battery (p=0.01) Conclusion: Video head impulse testing is comparable to caloric testing to assess vestibular function. Vestibular lesions may lead to cognitive deficits. Further research is needed to better understand the role of video head impulse testing in vestibular schwannoma.
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.publisherUniversity of Otago
dc.rightsAll items in OUR Archive are provided for private study and research purposes and are protected by copyright with all rights reserved unless otherwise indicated.
dc.subjectVestibular
dc.subjectSchwannoma
dc.subjectAcoustic
dc.subjectNeuroma
dc.subjectHIT
dc.subjectVideo-Oculography
dc.subjectVOR
dc.titleVestibular Function in Vestibular Schwannoma
dc.typeThesis
dc.date.updated2016-05-18T03:42:57Z
dc.language.rfc3066en
thesis.degree.disciplineDepartment of Medicine
thesis.degree.nameBachelor of Medical Science with Honours
thesis.degree.grantorUniversity of Otago
thesis.degree.levelHonours
otago.openaccessOpen
otago.evidence.presentYes
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