Chemistry
Recent Deposits
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Isoreticulation of an adamantane-based lithium framework
Isoreticulation is the “tweaking” of the structure of an already established metal-organic framework (MOF) to alter certain properties, while still maintaining the original parent topology. This work investigated the ... -
Towards Fluorescent Carbon Monoxide Releasing Molecules
This research project aimed to develop fluorescent analogues of the oCOm molecules reported by Larsen and co-workers.1 It was proposed that the attachment of phenanthrene-based fluorescent reporter groups to these CO ... -
Development of traceability tools based on metabolomics for milk products
Fraud is endemic throughout the food industry and a major concern to producers and consumers. Adulteration or substitution with an inferior product may cause economic or health problems. Milk is a foodstuff that is widely ... -
Thermoreversible hydrogels based on PEO stars
The aim of the project is to develop a range of hydrogels made from biocompatible monomers which could be used in various biomedical applications. The particular interest is on star-shaped block copolymers which consist ... -
The Pesticide Loss via Volatilisation (PLOVO) Model and an Environmental Fate Study of Chlorpyrifos
Pesticides are an important tool in modern crop management to ensure high quality and high yield food production. However, pesticide Volatilisation from agricultural fields can have a significant impact on non target, ... -
Chemistry of a Stable Vitamin C Glycoside in Apples (Malus spp.) and Other Fruit Crops
The primary aim of the research described in this thesis was to investigate an ascorbyl glycoside tentatively identified in crab apples (Malus sylvestris) by a non-targeted metabolomics study (unpublished thesis, J. Cho, ... -
Bridging the Gap: Synthesis of Bay-Annulated Hexa-peri-hexabenzocoronenes
This thesis consists of five chapters describing the bay-annulation of the planar hexa-peri-hexabenzocoronene towards a bowl-shaped hexa-peri-hexabenzocoronene where all six bay sites are annulated. Chapter one provides ... -
Carbon-rich coordination cages
This thesis consists of five chapters describing the synthesis and host-guest binding studies of various carbon-rich metallosupramolecular cages. Chapter 1 provides an introduction of the field of metallosupramolecular ... -
Understanding Semi-Volatile Pesticides Fate and Transport: Field and Laboratory Studies with Modelling Approach
The use of pesticides in the agricultural sector, alongside other technological advances, caused dramatic increases in crop yield but also accompanying increases in environmental concerns. Pesticide volatilisation and ... -
New macrocycles for polymerisation catalysis
This thesis concerns the synthesis of diphenylamine-based macrocycles for generating new dimetallic polymerisation catalysts. Chapter 1 introduces the target polymerisations we aim to catalyse, and reviews the current ... -
Modification of Catalytically Active and/or Switchable Complexes for Surface Attachment
The overall aim of this project was to take robust complexes which exhibit reversible redox, catalytic activity, or spin crossover (SCO), and design, prepare and characterise suitably functionalised analogues of them, in ... -
Crystal Engineering of Transition Metal Complexes Containing Triple Hydrogen Bond Synthons: Towards the Co-crystallisation of Complexes
The understanding of the structural features within molecular compounds that facilitate their intermolecular assembly by hydrogen bonding, either with themselves or with complementary species, is important for the construction ... -
Synthesis of oligosaccharides for functionalization of RHDV VLP
Virus-like particles (VLP) present a promising platform for antigen delivery in anticancer vaccines. Conjugation of rabbit hemorrhagic disease virus (RHDV) VLP and simple mannoside components have been shown to increase ... -
Investigation of Ligand Design for the Self-assembly of [2 + 2] Metallomacrocycles Towards Drug Delivery
Antimicrobial resistance has been a pressing issue in medical treatment for over twenty years. Metal-organic compounds have shown potential as an additional source of antimicrobial agents. Additionally, preliminary studies ... -
Tracing Nutrients and Contaminants in Nearshore Food Web
Sewage derived organic matter from domestic and municipal wastewater, promotes enhanced secondary productivity, eutrophication and trace metal contamination, reduction in oxygen levels, and biodiversity. It poses a potential ... -
Flavones from Cyclopropanes: Development of Methodology and the Total Synthesis of Integrin and (±)-Oxyisocyclointegrin
Cyclopropanes are important substrates in organic chemistry able to participate in many different classes of reactions which can be broadly classified as ring opening, cycloaddition and rearrangement reactions. The unique ... -
Marine anoxia during Oceanic Anoxic Event 2: Constraints from the southern palaeo-Pacific and Tethys Oceans using carbon- and uranium-isotope systems
The Cenomanian–Turonian anoxic event or ‘Oceanic Anoxic Event 2’ (OAE 2), occurring c. 94 million years ago, marks one of the most severe climatic disturbances in Earth’s history and is associated with widespread ocean ... -
Applications of α-Oxygenated Cyclopropanes in Organic Methodology
Chapter one firstly details the bonding and reactivity of cyclopropanes, and highlights these aspects in prior literature work. Furthermore the literature syntheses for the 1,3-oxazinone heterocycles, and how cyclopropanes ... -
Interaction of Charge Transfer States in Transition Metal Complexes
The photophysical properties of a range of transition metal 1,10-phenanthroline (phen) complexes have been investigated. A suite of electronic and vibrational spectroscopic techniques including steady state and transient ... -
A Synthetic Methodology for Accessing Ceramide Based iNKT Cell Agonists
It is well established that immunological surveillance is an important method by which cancer is controlled in healthy people. Cancer immunotherapy aims to exploit the power of the host immune system for the targeted ...