Chemistry
Recent Deposits
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Flavones from Cyclopropanes: Development of Methodology and the Total Synthesis of Integrin and (±)-Oxyisocyclointegrin
Cyclopropanes are important substrates in organic chemistry able to participate in many different classes of reactions which can be broadly classified as ring opening, cycloaddition and rearrangement reactions. The unique ... -
Marine anoxia during Oceanic Anoxic Event 2: Constraints from the southern palaeo-Pacific and Tethys Oceans using carbon- and uranium-isotope systems
The Cenomanian–Turonian anoxic event or ‘Oceanic Anoxic Event 2’ (OAE 2), occurring c. 94 million years ago, marks one of the most severe climatic disturbances in Earth’s history and is associated with widespread ocean ... -
Applications of α-Oxygenated Cyclopropanes in Organic Methodology
Chapter one firstly details the bonding and reactivity of cyclopropanes, and highlights these aspects in prior literature work. Furthermore the literature syntheses for the 1,3-oxazinone heterocycles, and how cyclopropanes ... -
Interaction of Charge Transfer States in Transition Metal Complexes
The photophysical properties of a range of transition metal 1,10-phenanthroline (phen) complexes have been investigated. A suite of electronic and vibrational spectroscopic techniques including steady state and transient ... -
A Synthetic Methodology for Accessing Ceramide Based iNKT Cell Agonists
It is well established that immunological surveillance is an important method by which cancer is controlled in healthy people. Cancer immunotherapy aims to exploit the power of the host immune system for the targeted ... -
"Click" Functionalised Ferrocene-based Molecular Actuators
This thesis describes the synthesis of 2-pyridyl-1,2,3-triazole functionalised ferrocene ligands, their coordination chemistry, and their ability to act as molecular actuators. It consists of five chapters. Chapter 1 ... -
Copper speciation in different marine ecosystems around New Zealand
Copper (Cu) is an important bioactive trace metal in the marine environment, acting as an essential micronutrient for many marine species. However, it can also be harmful at elevated concentrations, triggering sub-lethal ... -
Carbonylations with Bridged Carbonyl Compounds as CO donors
This thesis describes research carried out to develop a norbornadienone based organic carbon monoxide releasing molecule (CORM) as a safe, solid CO source for various carbonylation reactions. Reaction of 2,5-dimethyl-3,4 ... -
Functionalised Metal Nanoparticles for Surface Attachment Reactions
Surface attachment of functional molecules to metal nanoparticles can facilitate many useful applications such as molecular electronics.1-2 Preparing size-controlled stable nanoparticles with specific surface functionality ... -
N2 Dissociation Over Selected Pure Rare Earth Surfaces
N2 dissociation on a selection of rare earth (RE) elements (Nd, Sm, Eu, Yb) is studied to better understand a recent experimental observation that some rare earth nitrides (RENs) are able to form at ambient temperature and ... -
Redox Polymers for Bulk Gel Actuators
The objective of this study is to make an electroactive, relatively fast (moderate speed), durable, and self-contained polymer gel actuator at the centimetre scale using redox polymers. There are many prototype electric ... -
Polymer Monolayers for Chromium(III) (Hydr)oxide, with Antifouling Applications for Stainless Steel Surfaces
The intended purpose of this work is to form a more complete understanding of how to maintain pristine, foulant-resistant stainless steel surfaces in aqueous proteinaceous or microbial environments such as those found on ... -
Synthesis, Characterisation and Antimicrobial Studies of “Click” 2,6-bis(1,2,3-triazol-4-yl)pyridine Ruthenium(II) Complexes
The first chapter of this thesis outlines the problematic era we find ourselves in with regards to antimicrobial resistance, and relevant information about antimicrobial therapy. A possible route forward is discussed, and ... -
Donor-Acceptor Cyclopropanes as Building Blocks for the Synthesis of Natural Product Scaffolds
The first chapter of this thesis provides an introduction to natural products and describes how they are a valuable source of bioactive compounds, which feature heavily in clinically used drugs. The recently reported ... -
A Metallosupramolecular Approach to Responsive Polymer Gels using Pyridine-Hydrazones
The use of metal-induced conformational changes in pyridine-hydrazone crosslinkers to control the volumes of gels was complicated by the adaptive metallosupramolecular behaviour of the ligands. The combination of ... -
Spectroscopy of Donor-Acceptor Dyes
A number of organic donor-acceptor dyes were investigated using spectroscopic and computational methods. This class of materials can form charge-transfer excited-states which result in a number of interesting properties. ... -
Transition metal complexes of pyrazine-based bis-terdentate diamide ligands
The four symmetrical, closely related pyrazine-based bis-terdentate diamide ligands N,N'-bis(2-pyridylmethyl)pyrazine-2,3-dicarboxamide (H2 LM1), N,N'-bis[2-(2-pyridyl)ethyl]pyrazine-2,3-dicarboxamide (H2 LM2), ... -
Total Synthesis of (-)-Spiroleucettadine
One of a number of intriguing new alkaloids isolated from the Leucetta sp. sponge in 2004, spiroleucettadine displayed unique structural features on a restricted scaffold: a trans-fused 5,5-bicyclic ring system together ... -
Accessing Natural Product Scaffolds; A Top-Down and Bottom-Up Approach
Natural products, and natural product derivatives, have applications in both total synthesis and synthetic methodology, as well as having medical applications. Whilst many natural products possess suitable activity against ... -
Hydrogen Isotopes in New Zealand Soil: A method comparison
The spatial characteristic of stable hydrogen and oxygen isotope ratios of global precipitation has been widely investigated. This study extends that investigation to tracing the flow of hydrogen isotope ratio patterns ...