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pH responsive nanoparticles as versatile carriers for cancer chemotherapy and vaccination
Cancer is one of the leading causes of mortality and morbidity in the Western world. The anguish caused by cancer is exacerbated by current chemotherapeutic treatments as severe adverse effects can be caused by off-target ... -
Bending Form: Dynamic Content Within a Framework and the Recordings of the Beatles in the Mid-Sixties
This written exegesis, alongside three recorded albums, Pictures of Everyday, Baby Astronaut, and The Dunedin Electric Co., works to reconcile the analytic with implementation through a practice-as-research approach. The ... -
Development of fluorescent ligands for A1 adenosine receptor and cannabinoid receptors
Adenosine A1 receptor (A1AR), cannabinoid type 1 receptor (CB1R) and cannabinoid type 2 receptor (CB2R) are class A G protein-coupled receptors (GPCRs) and play important roles in human pathophysiological conditions such ... -
Neural basis of categorisation in a 30-million-year-old feathered reptilian dinosaur
Categorisation is a cognitive ability to group individual stimuli into different categorical groups based on their common features. The categorisation ability is not limited to human and non-human primates. Evidence ... -
Injured Migrant Study (IMS): A prospective study of post-injury outcomes in New Zealand
Background The burden of injury has been well documented, and migrants are more likely to have both higher risks of injury and experience poorer outcomes following injury compared to non-migrants. In New Zealand, a significant ... -
Population status and genetic diversity of the endemic black-billed gull Larus bulleri of New Zealand
The endangered black-billed gull (Larus bulleri) is endemic to New Zealand, and is the world’s most threatened gull species due to suspected large population declines. These gulls primarily rely on open gravel beds in ... -
Climate controls on the mass balance of Brewster Glacier, Southern Alps
Glaciers are highly sensitive indicators of climate variability. From the 1980’s to the early 2000’s, some glaciers in the Southern Alps experienced periods of advance; counter to global trends of glacier recession. These ... -
Hearing Galatians Today in Light of Dietrich Bonhoeffer's Theology of Freedom
In the epistle to the Galatians Paul tells the church, “For you were called to freedom, brothers and sisters; only do not use your freedom as an opportunity for self-indulgence, but through love become slaves to one another” ... -
A Foot in Both Worlds: The Bicultural Audience and Film in New Zealand
This Masters thesis works as a pilot project to provide a platform for the development of bicultural audience reception research in a New Zealand context. For the purpose of this study, a “bicultural” person is defined as ... -
Conservation Genetics of North Island Kōkako (Callaeas wilsoni)
Conservation genetics has recently been recognised as an important, although often overlooked, aspect of wildlife management. Applying molecular techniques and genetic concepts to management strategies has the potential ... -
The comparative assessment of patient safety at hospitals in New Zealand
Patient safety is the avoidance, prevention and amelioration of adverse outcomes or injuries stemming from the healthcare system. Patient safety is the most important constituent of quality and has become increasing important ... -
The Reception of Sean O'Casey's Early Works in New Zealand (1924–47): A Social, Cultural, and Political Reading of the Archive
This thesis recovers the New Zealand reception history of Sean O’Casey, the Irish working-class playwright who rose to prominence at the Dublin Abbey Theatre in the aftermath of the Irish revolutionary period. Until now, ... -
Physiological Arousal, Information Processing, Performance and Expertise in Expected and Unexpected Abnormal Flight Events: An Empirical Investigation.
Aviation accident reports indicate that preventable incidents are developing into tragedies with pilots responding incorrectly to well-trained events e.g. engine failures. Recent research suggests that startle (an autonomic ... -
Arte para el pueblo: A Look at the Postcolonial Potential of the Murals of los tres grandes and Their Value and Limits as Emancipatory Visual Narratives
Los tres grandes were the leading members of the Mexican Mural Renaissance, a government sponsored public art movement that emerged from the Mexican Revolution of 1910-1920. Commonly labelled ‘architects of the nation’, ... -
Hop aroma in beer - changes in the flavour profile associated with different yeast strains and fermentation parameters
Beer has a complex flavour profile made up of hundreds of compounds, derived from its ingredients and changes that occur during the production process. Although beer flavour has been extensively researched, some of the ... -
Tattooing, bodies and women : notions of resistance
Tattooing is a form of body modification that has existed in society for thousands of years. All societies place importance on the body, and bodies are modified throughout the world by a variety of practices, of which ... -
Arsenic : the influence of natural parameters on its oxidation and mobilization in gold mines
Arsenic (As) is a common constituent of mining and geothermal systems. Literature has described the element as a toxin and human carcinogen particularly when it exists as As (III). Wairakei (North Island, New Zealand) ... -
Re-staging history : historiographic drama from New Zealand and Australia
Since the 1980s, there has been an increasing emphasis on drama, in live theatre and on film, which re-addresses the ways in which the post-colonial histories of Australia and New Zealand have been written. Why is there ... -
Exchange of nutrients from Big Glory Bay, Stewart Island
Big Glory bay is a semi-enclosed bay located in the south-east of Paterson Inlet, Stewart Island. The bay has been used for commercial sea cage rearing of chinook salmon (Oncorhynchus tshawytscha Walbaum) since 1981 and ... -
Prolactin receptor expression in the mouse brain
We used a novel knock‐in mouse strain in which Cre recombinase is expressed together with the long isoform of the Prlr using an internal ribosome entry site (IRES). By crossing this Prlr‐IRES‐Cre mouse with a tau green ...