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An Exploration of University Students’ Lived Experience with Alcohol within the Contexts of Family, Peers, and Orientation
Undergraduate students in New Zealand universities demonstrate high rates of hazardous drinking, as do other undergraduates in many universities around the world. There are a number of factors related to hazardous drinking ... -
Atherogenic Index In Plasma and Risk of Cardiovascular Events
As dyslipidaemia is a prominent CVD risk factor, improvements in its management are crucial, as dyslipidaemia (quantified by hypercholesterolemia and treated with statins), incompletely addresses the residual CVD risk ... -
Arterial Hypertension. Consume Carbon Monoxide?
Epithelial sodium channels (ENaC) are generally responsible for the passive movement of sodium ions through the apical cell membrane of salt absorbing epithelia. Canonical ENaC is composed of three homologous subunits, ... -
Characterisation of Arcuate Nucleus Projections to the Paraventricular Nucleus of Thalamus
The metabolic state (fed or hungry) has been shown to influence varying responses to food-associated cues. Recent studies reveal that the paraventricular nucleus of the thalamus (PVT) may play a critical role as it receives ... -
A Novel Oocyte Cryopreservation Method using High Pressure Freezing
Oocyte cryopreservation (egg freezing) involves freezing a female’s oocytes in order to preserve her fertility. These oocytes can later be thawed and fertilised in vitro when she is ready to begin fertility treatment. Women ... -
Bacterial regulation of early activation of mucosal-associated invariant T (MAIT) cells
Mucosal-associated invariant T (MAIT) cells are a population of CD8+ innate-like T cells that play an important role in the immune response to bacterial infections. Being characterised by the expression of a unique ... -
Does the production value of a short science video hosted on YouTube influence how much the desired audience is likely to enjoy and engage with it?
This thesis continues the research of Welbourne and Grant (2016) within the field of science communication on YouTube, by following the study that Figueiredo, Almeida, & Benevenuto designed to evaluate whether content ... -
The α-Adrenergic System and CaMKII in Diabetic Heart Disease
The relationship between diabetes mellitus and heart disease is widely documented, with heart disease being the main cause of mortality in diabetic patients. Diabetes impairs the autonomic nervous system, leading to an ... -
The Role of α-ENaC and δ-ENaC in Breast Cancer Cell Migration
Breast cancer is an important disease worldwide, primarily affecting women, and is the most common and deadliest form of female cancer. This is reflected in New Zealand’s population as breast cancer has high incidence and ... -
Candidate Compounds for the Chemoprevention of Hereditary Diffuse Gastric Cancer
Hereditary diffuse gastric cancer (HDGC) is a cancer syndrome caused by germline mutations in the tumour suppressor gene CDH1, which encodes the cell-cell adhesion protein E-cadherin. Mutations in CDH1 lead to increased ... -
Investigation into the Anticancer Mechanism of Action of Novel 4-Substituted Phenylthiazoles and Antihelminthic Benzimidazoles
Recently, two novel 4-substituted phenylthiazoles, D1 and D2, have been synthesised based upon the marine bacterial secondary metabolite anithiactin A/thiasporine C, and shown to be cytotoxic towards cancer cells below 100 ... -
New macrocycles for polymerisation catalysis
This thesis concerns the synthesis of diphenylamine-based macrocycles for generating new dimetallic polymerisation catalysts. Chapter 1 introduces the target polymerisations we aim to catalyse, and reviews the current ... -
Mediation and Reciprocity: ESL Learner Writing Development through Error Correction
The provision of corrective feedback (CF) on errors in essay writing is a controversial topic. In second language acquisition (SLA), the controversy focuses whether CF contributes to the development of language systems, ... -
Hidden Markov Models for Time-Inhomogeneous and Incompletely Observed Point Processes
Many point processes such as earthquakes or volcanic eruptions usually have incomplete records with the degree of incompleteness varying over time. Consequently, hazard estimation from such time-inhomogeneous incomplete ... -
Validation and Characterisation of Novel miRNAs Identified in the E15.5 Mouse Brain
MicroRNAs (miRNAs) are small noncoding elements that downregulate gene expression and play an important role in maintaining robust neurodevelopment. Since abnormal expression of miRNAs has been associated with disorders ... -
Bond strength of a direct composite resin to resin-matrix ceramic materials with four surface treatments
Background Aesthetic demands have popularized the use of dental ceramic and indirect composite resin materials in modern dentistry. The introduction of dental CAD/CAM technology expanded the use of these materials even ... -
An Empire at War: Economic Disparities in the Roman Empire 260-275 CE
The third century CE was a period of turmoil for the Roman Empire, as can be seen for example in the disastrous years between 260-275 CE. The emperor Valerian had been captured by the Sasanids, and Rome was left scrambling ... -
Vital Bleaching (At-home, In-office, In-office + At home), Colour Change and Oral Health Related Quality of Life
Abstract Objectives This randomised clinical trial compared tooth colour change, participant satisfaction and Oral Health-Related Quality of Life (OHRQoL) following application of at-home, in-office and combined at-home ... -
BRAF mutations in ameloblastoma: Correlation with clinical and histopathological features and behaviour
Background: The invasive nature of ameloblastoma necessitates tumour-free surgical margins to minimise recurrence and thereby ensure improved prognosis. The vast majority of ameloblastomas originate centrally, and surgical ... -
Neuropilin-1 expression in the tumour microenvironment of oral squamous cell carcinoma
Background: Neuropilin-1 (Nrp-1) is a transmembrane glycoprotein involved in multiple biologic and pathologic processes including carcinogenesis. It is widely expressed in cancers where it has been correlated with poorer ...