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Ion homeostasis in Mycobacterium smegmatis
Microorganisms must maintain equilibrium and intracellular availability of ions for growth and persistence in a range of environments, either in the face of scarce resources or excesses, whereby they must buffer, exclude ... -
Application of second and third generation sequencing in pharmacogenetics
The next generation sequencing technologies have advanced pharmacogenetics by enabling rapid assessment of the entire exome or even whole genome for associations between variants or gene regions with drug response. Third ... -
The impact of mobile mindfulness meditation on mental health and well-being in university students
Mindfulness meditation is a common psychotherapy informed by Buddhist mindfulness that is gaining traction outside of the clinic. One area that is particularly popular is mobile mindfulness meditation, the use of applications ... -
Evaluation of a pilot breast cancer screening programme
A pilot mammographic breast cancer screening programme was established in 1991 for women aged fifty to sixty-four living in Otago and Southland. The pilot programme was evaluated to measure the acceptability, effectiveness, ... -
Manipulation of the host cell cycle by murine norovirus VPg
Human norovirus (HuNV) is a leading cause of acute gastroenteritis worldwide. Despite advances in HuNV cell culture the virus remains difficult to study in the laboratory. Murine norovirus (MNV) is routinely utilised as a ... -
Climate change and behaviour change : empowering youth action through narrative
This thesis is a review of the literature spanning multiple disciplines to provide an overview of climate change science in the global and New Zealand context, its implications, and a context for action amongst young New ... -
Hierarchical capture-recapture models
A defining feature of capture-recapture is missing data due to imperfect detection of individuals. The standard approach used to deal with the missing data is to integrate (or sum) over all the possible unknown values. The ... -
Ruth France and the male monolith
This thesis explores how a promising writer of the 1950s and 1960s did not fulfill her promise because the literary climate of New Zealand was controlled by male writers who were mostly out of sympathy with women's writing. ... -
Effect of sitting postures on the hemodynamics of the popliteal and femoral veins
If one were to choose a single object to epitomise the discipline of Design, it could easily be the chair. Most buildings, vehicles or machines contain them. Many of us find ourselves compelled to sit in seats or chairs ... -
Public health organization in four rural districts in Western Samoa.
In the light of the modern world, the inhabitants of underdeveloped countries, of which Samoa in the strict sense of the word is one, of them, frequently in their lower level of knowledgeable resources, referred to foreign ... -
Titles and their entitlements
The concern is with titles, and what they are entitled to do and be. The chapters that make up the thesis are about categories of titles, and so the continuity between chapters is one of theme. Chapter One proposes a point ... -
Marine spatial planning in the Marlborough Sounds
The Marlborough Sounds is an area located at the top of the South Island, and is made up of around 1400 kilometres of coastline. Within this area, there is a wide range of uses in the marine environment. The Sounds is an ... -
Transgenerational plasticity and acclimation of tropical sea urchins to ocean warming and acidification
Anthropogenic CO2 emissions are causing the oceans to simultaneously warm and become increasingly acidic, with rates of change that are putting evolutionary pressure on many marine organisms. As a result, both short-term ... -
Cholinergic modulation of cortical sensory-evoked responses
Cholinergic inputs to the cortex from the basal forebrain are essential for performing complex behaviours that require precise integration of sensory and motor information. However, the role of the basal forebrain cholinergic ... -
Understanding altered intrinsic heart rate in type 2 diabetes
Heart rate (HR) is generated by sinoatrial node (SAN) intrinsic pacemaking and modulated by autonomic innervation. Within the SAN, intrinsic (ex vivo) HR is determined by the mutual entrainment of the sarcolemmal voltage ... -
Constitutive PD-L1 expression in melanoma
Treatment of melanoma based on targeted therapy and immunotherapy has dramatically advanced over the past decade. Advances in targeted therapy have been based on inhibition of the MAPK pathway while for immunotherapy, ... -
Malaysian women's narratives of navigating careers following international study in New Zealand
This thesis presents a narrative study that explored 14 Malaysian women’s narratives of navigating careers in Malaysia following international study in New Zealand. The women were part of a Twinned In-Service Teacher ... -
Tectonic geomorphology of the Rock and Pillar Range and Taieri Ridge, Otago, New Zealand
In the South Island of New Zealand, east Otago is a region of low seismicity with many potentially active faults, and profound data gaps. I use geomorphic observations, and Optically Stimulated Luminescence (OSL) dating ... -
The survivor imperative: an autoethnography of secondary victimization after sexual violence
In this thesis, I explore the lived repercussions of dominant discourses around victimhood and survivorship, informed by rape myths, by focusing on interpersonal responses to victims of sexual violence and the consequences ... -
Persistent musculoskeletal pain in individuals with inflammatory bowel diseases
Background: Pain affects over 70% of individuals with inflammatory bowel disease (IBD), with abdominal and musculoskeletal (MSK) pain representing the most common complaints identified by patients. To date most studies in ...